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GBA haploinsufficiency accelerates alpha-synuclein pathology with altered lipid metabolism in a prodromal model of Parkinson's disease.
Ikuno, Masashi; Yamakado, Hodaka; Akiyama, Hisako; Parajuli, Laxmi Kumar; Taguchi, Katsutoshi; Hara, Junko; Uemura, Norihito; Hatanaka, Yusuke; Higaki, Katsumi; Ohno, Kousaku; Tanaka, Masaki; Koike, Masato; Hirabayashi, Yoshio; Takahashi, Ryosuke.
Afiliação
  • Ikuno M; Department of Neurology Kyoto University Graduate School of Medicine, Kyoto, Japan.
  • Yamakado H; Department of Neurology Kyoto University Graduate School of Medicine, Kyoto, Japan.
  • Akiyama H; Laboratory for Molecular Membrane Neuroscience, RIKEN Brain Science Institute, Saitama, Japan.
  • Parajuli LK; Department of Cell Biology and Neuroscience, Juntendo University Graduate School of Medicine, Tokyo, Japan.
  • Taguchi K; Department of Anatomy and Neurobiology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.
  • Hara J; Department of Neurology Kyoto University Graduate School of Medicine, Kyoto, Japan.
  • Uemura N; Department of Neurology Kyoto University Graduate School of Medicine, Kyoto, Japan.
  • Hatanaka Y; Department of Neurology Kyoto University Graduate School of Medicine, Kyoto, Japan.
  • Higaki K; Division of Functional Genomics, Research Center for Bioscience and Technology, Faculty of Medicine, Tottori University, Tottori, Japan.
  • Ohno K; Sanin Rosai Hospital, Tottori, Japan.
  • Tanaka M; Department of Anatomy and Neurobiology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.
  • Koike M; Department of Cell Biology and Neuroscience, Juntendo University Graduate School of Medicine, Tokyo, Japan.
  • Hirabayashi Y; Laboratory for Molecular Membrane Neuroscience, RIKEN Brain Science Institute, Saitama, Japan.
  • Takahashi R; Department of Neurology Kyoto University Graduate School of Medicine, Kyoto, Japan.
Hum Mol Genet ; 28(11): 1894-1904, 2019 06 01.
Article em En | MEDLINE | ID: mdl-30689867
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Parkinson / Alfa-Sinucleína / Glucosilceramidase Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals / Humans Idioma: En Revista: Hum Mol Genet Ano de publicação: 2019 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Parkinson / Alfa-Sinucleína / Glucosilceramidase Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals / Humans Idioma: En Revista: Hum Mol Genet Ano de publicação: 2019 Tipo de documento: Article