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Combined treatment with HMGN1 and anti-CD4 depleting antibody reverses T cell exhaustion and exerts robust anti-tumor effects in mice.
Chen, Chang-Yu; Ueha, Satoshi; Ishiwata, Yoshiro; Yokochi, Shoji; Yang, De; Oppenheim, Joost J; Ogiwara, Haru; Shichino, Shigeyuki; Deshimaru, Shungo; Shand, Francis H W; Shibayama, Shiro; Matsushima, Kouji.
Afiliação
  • Chen CY; Division of Molecular Regulation of Inflammatory and Immune Diseases, Research Institute for Biomedical Sciences, Tokyo University of Science, Chiba, Japan.
  • Ueha S; Department of Molecular Preventive Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
  • Ishiwata Y; Division of Molecular Regulation of Inflammatory and Immune Diseases, Research Institute for Biomedical Sciences, Tokyo University of Science, Chiba, Japan.
  • Yokochi S; Department of Molecular Preventive Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
  • Yang; Division of Molecular Regulation of Inflammatory and Immune Diseases, Research Institute for Biomedical Sciences, Tokyo University of Science, Chiba, Japan.
  • Oppenheim JJ; Department of Molecular Preventive Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
  • Ogiwara H; Division of Molecular Regulation of Inflammatory and Immune Diseases, Research Institute for Biomedical Sciences, Tokyo University of Science, Chiba, Japan.
  • Shichino S; Department of Molecular Preventive Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
  • Deshimaru S; Cancer and Inflammation Program, Center for Cancer Research, National Cancer Institute at Frederick, Frederick, MD, USA.
  • Shand FHW; Cancer and Inflammation Program, Center for Cancer Research, National Cancer Institute at Frederick, Frederick, MD, USA.
  • Shibayama S; Division of Molecular Regulation of Inflammatory and Immune Diseases, Research Institute for Biomedical Sciences, Tokyo University of Science, Chiba, Japan.
  • Matsushima K; Department of Molecular Preventive Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
J Immunother Cancer ; 7(1): 21, 2019 01 29.
Article em En | MEDLINE | ID: mdl-30696484
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Linfócitos T CD4-Positivos / Linfócitos T CD8-Positivos / Proteína HMGN1 / Anticorpos / Neoplasias Limite: Animals Idioma: En Revista: J Immunother Cancer Ano de publicação: 2019 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Linfócitos T CD4-Positivos / Linfócitos T CD8-Positivos / Proteína HMGN1 / Anticorpos / Neoplasias Limite: Animals Idioma: En Revista: J Immunother Cancer Ano de publicação: 2019 Tipo de documento: Article