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Small Molecule SOS1 Agonists Modulate MAPK and PI3K Signaling via Independent Cellular Responses.
Akan, Denis T; Howes, Jennifer E; Sai, Jiqing; Arnold, Allison L; Beesetty, Yugandhar; Phan, Jason; Olejniczak, Edward T; Waterson, Alex G; Fesik, Stephen W.
Afiliação
  • Akan DT; Department of Biochemistry , Vanderbilt University School of Medicine , 2215 Garland Avenue, 607 Light Hall , Nashville , Tennessee 37232-0146 , United States.
  • Howes JE; Department of Biochemistry , Vanderbilt University School of Medicine , 2215 Garland Avenue, 607 Light Hall , Nashville , Tennessee 37232-0146 , United States.
  • Sai J; Department of Biochemistry , Vanderbilt University School of Medicine , 2215 Garland Avenue, 607 Light Hall , Nashville , Tennessee 37232-0146 , United States.
  • Arnold AL; Department of Biochemistry , Vanderbilt University School of Medicine , 2215 Garland Avenue, 607 Light Hall , Nashville , Tennessee 37232-0146 , United States.
  • Beesetty Y; Department of Biochemistry , Vanderbilt University School of Medicine , 2215 Garland Avenue, 607 Light Hall , Nashville , Tennessee 37232-0146 , United States.
  • Phan J; Department of Biochemistry , Vanderbilt University School of Medicine , 2215 Garland Avenue, 607 Light Hall , Nashville , Tennessee 37232-0146 , United States.
  • Olejniczak ET; Department of Biochemistry , Vanderbilt University School of Medicine , 2215 Garland Avenue, 607 Light Hall , Nashville , Tennessee 37232-0146 , United States.
  • Waterson AG; Department of Pharmacology , Vanderbilt University School of Medicine , 2215 Garland Avenue, 607 Light Hall , Nashville , Tennessee 37232-0146 , United States.
  • Fesik SW; Department of Chemistry , Vanderbilt University , 2215 Garland Avenue, 607 Light Hall , Nashville , Tennessee 37232-0146 , United States.
ACS Chem Biol ; 14(3): 325-331, 2019 03 15.
Article em En | MEDLINE | ID: mdl-30735352
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Quinazolinas / Benzimidazóis / Fosfatidilinositol 3-Quinases / Quinases de Proteína Quinase Ativadas por Mitógeno / Proteína SOS1 / Indóis Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: ACS Chem Biol Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Quinazolinas / Benzimidazóis / Fosfatidilinositol 3-Quinases / Quinases de Proteína Quinase Ativadas por Mitógeno / Proteína SOS1 / Indóis Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: ACS Chem Biol Ano de publicação: 2019 Tipo de documento: Article