Methyl-CpG Binding Domain Protein 2 Inhibits the Malignant Characteristic of Lung Adenocarcinoma through the Epigenetic Modulation of 10 to 11 Translocation 1 and miR-200s.

Pei, Yao-Fei; Xu, Xiang-Nan; Wang, Zhi-Fei; Wang, Fu-Wei; Wu, Wei-Ding; Geng, Jun-Feng; Liu, Xi-Qiang

Pei, Yao-Fei; Xu, Xiang-Nan; Wang, Zhi-Fei; Wang, Fu-Wei; Wu, Wei-Ding; Geng, Jun-Feng; Liu, Xi-Qiang.

Afiliação

Pei YF; Department of Thoracic Surgery, Shanghai Chest Hospital, Shanghai Jiaotong University, Shanghai, People's Republic of China.
Xu XN; Department of Thoracic Surgery, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, People's Republic of China.
Wang ZF; Department of Hepatopancreatobiliary Surgery and Minimally Invasive Surgery, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, People's Republic of China; Key Laboratory of Tumor Molecular Diagnosis and Individualized Medicine of Zhejiang Province, Hangz
Wang FW; Key Laboratory of Tumor Molecular Diagnosis and Individualized Medicine of Zhejiang Province, Hangzhou, People's Republic of China; Key Laboratory of Gastroenterology of Zhejiang Province, Hangzhou, People's Republic of China.
Wu WD; Department of Hepatopancreatobiliary Surgery and Minimally Invasive Surgery, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, People's Republic of China; Key Laboratory of Tumor Molecular Diagnosis and Individualized Medicine of Zhejiang Province, Hangz
Geng JF; Department of Thoracic Surgery, Shanghai Chest Hospital, Shanghai Jiaotong University, Shanghai, People's Republic of China. Electronic address: filiks@msn.com.
Liu XQ; Department of Hepatopancreatobiliary Surgery and Minimally Invasive Surgery, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, People's Republic of China; Key Laboratory of Tumor Molecular Diagnosis and Individualized Medicine of Zhejiang Province, Hangz

Am J Pathol ; 189(5): 1065-1076, 2019 05.

Article em En | MEDLINE | ID: mdl-30735628

Assuntos

Adenocarcinoma de Pulmão/patologia; Biomarcadores Tumorais/genética; Proteínas de Ligação a DNA/metabolismo; Epigênese Genética; Regulação Neoplásica da Expressão Gênica; MicroRNAs/genética; Oxigenases de Função Mista/genética; Proteínas Proto-Oncogênicas/genética; Adenocarcinoma de Pulmão/genética; Adenocarcinoma de Pulmão/metabolismo; Apoptose; Movimento Celular; Proliferação de Células; Metilação de DNA; Proteínas de Ligação a DNA/genética; Feminino; Seguimentos; Humanos; Neoplasias Pulmonares/genética; Neoplasias Pulmonares/metabolismo; Neoplasias Pulmonares/patologia; Masculino; Pessoa de Meia-Idade; Prognóstico; Regiões Promotoras Genéticas; Células Tumorais Cultivadas

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Biomarcadores Tumorais / Regulação Neoplásica da Expressão Gênica / Proteínas Proto-Oncogênicas / MicroRNAs / Epigênese Genética / Proteínas de Ligação a DNA / Adenocarcinoma de Pulmão / Oxigenases de Função Mista Tipo de estudo: Observational_studies / Prognostic_studies Limite: Female / Humans / Male / Middle aged Idioma: En Revista: Am J Pathol Ano de publicação: 2019 Tipo de documento: Article

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