Population Pharmacokinetic Estimates Suggest Elevated Clearance and Distribution Volume of Desethylamodiaquine in Pediatric Patients with Sickle Cell Disease Treated with Artesunate-Amodiaquine.

Adjei, George O; Amponsah, Seth K; Goka, Bamenla Q; Enweronu-Laryea, Christabel; Renner, Lorna; Sulley, Abdul Malik; Alifrangis, Michael; Kurtzhals, Jorgen A L

Adjei, George O; Amponsah, Seth K; Goka, Bamenla Q; Enweronu-Laryea, Christabel; Renner, Lorna; Sulley, Abdul Malik; Alifrangis, Michael; Kurtzhals, Jorgen A L.

Afiliação

Adjei GO; Centre for Tropical Clinical Pharmacology and Therapeutics, School of Medicine and Dentistry, College of Health Sciences, University of Ghana, Accra, Ghana.
Amponsah SK; Department of Pharmacology and Toxicology, School of Pharmacy, College of Health Sciences, University of Ghana, Accra, Ghana.
Goka BQ; Department of Child Health, School of Medicine and Dentistry, College of Health Sciences, University of Ghana, Accra, Ghana.
Enweronu-Laryea C; Department of Child Health, School of Medicine and Dentistry, College of Health Sciences, University of Ghana, Accra, Ghana.
Renner L; Department of Child Health, School of Medicine and Dentistry, College of Health Sciences, University of Ghana, Accra, Ghana.
Sulley AM; Centre for Tropical Clinical Pharmacology and Therapeutics, School of Medicine and Dentistry, College of Health Sciences, University of Ghana, Accra, Ghana.
Alifrangis M; Centre for Medical Parasitology at Department of International Health, Immunology and Microbiology University of Copenhagen and Department of Clinical Microbiology and Department of Infectious Diseases, Copenhagen University Hospital (Rigshospitalet), Copenhagen, Denmark.
Kurtzhals JAL; Centre for Medical Parasitology at Department of International Health, Immunology and Microbiology University of Copenhagen and Department of Clinical Microbiology and Department of Infectious Diseases, Copenhagen University Hospital (Rigshospitalet), Copenhagen, Denmark.

Curr Ther Res Clin Exp ; 90: 9-15, 2019.

Article em En | MEDLINE | ID: mdl-30766619

Palavras-chave

Clearance; Desethylamodiaquine; Sickle cell disease

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 3_ND Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Aspecto: Patient_preference Idioma: En Revista: Curr Ther Res Clin Exp Ano de publicação: 2019 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google