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Rho-kinase inhibitor coupled to peptide-modified albumin carrier reduces portal pressure and increases renal perfusion in cirrhotic rats.
Klein, Sabine; Frohn, Franziska; Magdaleno, Fernando; Reker-Smit, Catharina; Schierwagen, Robert; Schierwagen, Irela; Uschner, Frank Erhard; van Dijk, Fransien; Fürst, Dieter O; Djudjaj, Sonja; Boor, Peter; Poelstra, Klaas; Beljaars, Leonie; Trebicka, Jonel.
Afiliação
  • Klein S; Department of Internal Medicine I, University of Bonn, Bonn, Germany.
  • Frohn F; Department of Internal Medicine I, Goethe University Frankfurt, Frankfurt, Germany.
  • Magdaleno F; Department of Internal Medicine I, University of Bonn, Bonn, Germany.
  • Reker-Smit C; Department of Internal Medicine I, University of Bonn, Bonn, Germany.
  • Schierwagen R; Department of Pharmacokinetics, Toxicology and Targeting, Groningen Research Institute for Pharmacy, University of Groningen, Groningen, Netherlands.
  • Schierwagen I; Department of Internal Medicine I, University of Bonn, Bonn, Germany.
  • Uschner FE; Department of Internal Medicine I, Goethe University Frankfurt, Frankfurt, Germany.
  • van Dijk F; Institute for Cell Biology, Department of Molecular Cell Biology, University of Bonn, Bonn, Germany.
  • Fürst DO; Department of Internal Medicine I, University of Bonn, Bonn, Germany.
  • Djudjaj S; Department of Internal Medicine I, Goethe University Frankfurt, Frankfurt, Germany.
  • Boor P; Department of Pharmacokinetics, Toxicology and Targeting, Groningen Research Institute for Pharmacy, University of Groningen, Groningen, Netherlands.
  • Poelstra K; Institute for Cell Biology, Department of Molecular Cell Biology, University of Bonn, Bonn, Germany.
  • Beljaars L; Institute of Pathology, RWTH University of Aachen, Aachen, Germany.
  • Trebicka J; Institute of Pathology, RWTH University of Aachen, Aachen, Germany.
Sci Rep ; 9(1): 2256, 2019 02 19.
Article em En | MEDLINE | ID: mdl-30783172
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Portadores de Fármacos / Pressão na Veia Porta / Inibidores Enzimáticos / Quinases Associadas a rho / Albumina Sérica Humana / Rim / Cirrose Hepática Limite: Animals / Humans / Male Idioma: En Revista: Sci Rep Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Portadores de Fármacos / Pressão na Veia Porta / Inibidores Enzimáticos / Quinases Associadas a rho / Albumina Sérica Humana / Rim / Cirrose Hepática Limite: Animals / Humans / Male Idioma: En Revista: Sci Rep Ano de publicação: 2019 Tipo de documento: Article