APOBEC3 Host Restriction Factors of HIV-1 Can Change the Template Switching Frequency of Reverse Transcriptase.

Adolph, Madison B; Ara, Anjuman; Chelico, Linda

Adolph, Madison B; Ara, Anjuman; Chelico, Linda.

Afiliação

Adolph MB; Department of Biochemistry, Microbiology, and Immunology, University of Saskatchewan, Saskatoon, Saskatchewan S7N 5E5, Canada; Department of Biochemistry, Vanderbilt University, Nashville, TN 37232, USA.
Ara A; Department of Biochemistry, Microbiology, and Immunology, University of Saskatchewan, Saskatoon, Saskatchewan S7N 5E5, Canada; Saskatchewan Cancer Agency and Division of Oncology, College of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan S7N 5E5, Canada.
Chelico L; Department of Biochemistry, Microbiology, and Immunology, University of Saskatchewan, Saskatoon, Saskatchewan S7N 5E5, Canada. Electronic address: linda.chelico@usask.ca.

J Mol Biol ; 431(7): 1339-1352, 2019 03 29.

Article em En | MEDLINE | ID: mdl-30797859

Assuntos

Citidina Desaminase/metabolismo; Transcriptase Reversa do HIV/metabolismo; HIV-1/genética; HIV-1/metabolismo; Desaminases APOBEC; Desaminase APOBEC-3G/metabolismo; Aminoidrolases/metabolismo; Citidina Desaminase/genética; Citosina Desaminase/metabolismo; Proteínas de Ligação a DNA/metabolismo; Desaminação; Humanos; Replicação Viral

Palavras-chave

DNA synthesis; enzymeDNA interactions; polymerase; proviral DNA integration; retroviral recombination

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: HIV-1 / Citidina Desaminase / Transcriptase Reversa do HIV Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: J Mol Biol Ano de publicação: 2019 Tipo de documento: Article

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