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Pd/Cu-Catalyzed Cascade C(sp3)-H Arylation and Intramolecular C-N Coupling: A One-Pot Synthesis of 3,4-2 H-Quinolinone Skeletons.
Xiao, Han-Zhi; Wang, Wen-Shu; Sun, Yu-Song; Luo, Hao; Li, Bo-Wen; Wang, Xiao-Dong; Lin, Wei-Li; Luo, Fei-Xian.
Afiliação
  • Xiao HZ; College of Life and Environment Science , §MUC Center on Translational Neuroscience , and ¶Experimental Center of Chemistry , Minzu University of China , Beijing 100081 , China.
  • Wang WS; College of Life and Environment Science , §MUC Center on Translational Neuroscience , and ¶Experimental Center of Chemistry , Minzu University of China , Beijing 100081 , China.
  • Sun YS; College of Life and Environment Science , §MUC Center on Translational Neuroscience , and ¶Experimental Center of Chemistry , Minzu University of China , Beijing 100081 , China.
  • Luo H; College of Life and Environment Science , §MUC Center on Translational Neuroscience , and ¶Experimental Center of Chemistry , Minzu University of China , Beijing 100081 , China.
  • Li BW; College of Life and Environment Science , §MUC Center on Translational Neuroscience , and ¶Experimental Center of Chemistry , Minzu University of China , Beijing 100081 , China.
  • Wang XD; College of Life and Environment Science , §MUC Center on Translational Neuroscience , and ¶Experimental Center of Chemistry , Minzu University of China , Beijing 100081 , China.
  • Lin WL; College of Life and Environment Science , §MUC Center on Translational Neuroscience , and ¶Experimental Center of Chemistry , Minzu University of China , Beijing 100081 , China.
  • Luo FX; College of Life and Environment Science , §MUC Center on Translational Neuroscience , and ¶Experimental Center of Chemistry , Minzu University of China , Beijing 100081 , China.
Org Lett ; 21(6): 1668-1671, 2019 03 15.
Article em En | MEDLINE | ID: mdl-30801191
In this letter, we successfully explored a cascade Pd/Cu-catalyzed intermolecular C(sp3)-H arylation of amides and intramolecular C-N coupling reaction. This method provides a one-pot strategy to synthesize 3,4-2 H-quinolinone with good regioselectivity of C-H arylation and C-N coupling from C-I and C-X bonds from readily available starting materials.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Org Lett Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Org Lett Ano de publicação: 2019 Tipo de documento: Article