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Personalized medicine with IgGAM compared with standard of care for treatment of peritonitis after infectious source control (the PEPPER trial): study protocol for a randomized controlled trial.
Kalvelage, Christina; Zacharowski, Kai; Bauhofer, Artur; Gockel, Ulrich; Adamzik, Michael; Nierhaus, Axel; Kujath, Peter; Eckmann, Christian; Pletz, Mathias W; Bracht, Hendrik; Simon, Tim-Philipp; Winkler, Michael; Kindgen-Milles, Detlef; Albertsmeier, Markus; Weigand, Markus; Ellger, Björn; Ragaller, Maximilian; Ullrich, Roman; Marx, Gernot.
Afiliação
  • Kalvelage C; Center for Translational and Clinical Research Aachen, RWTH Aachen University, Pauwelsstr. 30, 52074, Aachen, Germany.
  • Zacharowski K; Department of Anaesthesiology, Intensive Care Medicine and Pain Therapy, University Hospital Frankfurt, Frankfurt, Germany.
  • Bauhofer A; Corporate Medical Affairs, Biotest AG, Landsteinerstr. 5, 63303, Dreieich, Germany.
  • Gockel U; Medical Affairs Central Europe, Biotest AG, Landsteinerstr. 5, 63303, Dreieich, Germany.
  • Adamzik M; Department of Anesthesiology, Intensive Care Medicine and Pain Therapy, Ruhr-Universität Bochum, In der Schornau 23-25, 44892, Bochum, Germany.
  • Nierhaus A; Department of Intensive Care Medicine, University Hospital Hamburg-Eppendorf, Martinistraße 52, 20246, Hamburg, Germany.
  • Kujath P; Department of Surgery, University of Schleswig-Holstein, Ratzeburger Allee 160, 23538, Lübeck, Germany.
  • Eckmann C; Department of General, Visceral, and Thoracic Surgery, Klinikum Peine Academic Hospital of Medical University Hannover, Virchowstraße 8h, 31226, Peine, Germany.
  • Pletz MW; Center for Infectious Diseases and Infection Control, Jena University Hospital, Erlanger Allee 101, 07747, Jena, Germany.
  • Bracht H; Department of Anaesthesiology, University Ulm, Albert Einstein Allee 23, 89081, Ulm, Germany.
  • Simon TP; Department of Intensive Care and Intermediate Care, University Hospital RWTH Aachen, Pauwelsstr.30, 52074, Aachen, Germany.
  • Winkler M; Department of General, Visceral and Transplantation Surgery, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany.
  • Kindgen-Milles D; Department of Anaesthesiology, Düsseldorf University Hospital, Moorenstr. 5, 40225, Düsseldorf, Germany.
  • Albertsmeier M; Department of Anaesthesiology, Ludwig-Maximilians-University of Munich, Marchioninistrasse 15, 81377, Munich, Germany.
  • Weigand M; Department of Anesthesiology, Heidelberg University Hospital, Im Neuenheimer Feld 110, 69120, Heidelberg, Germany.
  • Ellger B; Department of Anesthesiology, Intensive Care and Pain Medicine, Klinikum Westfalen, Am Knappschaftskrankenhaus 1, 44309, Dortmund, Germany.
  • Ragaller M; Department of Anesthesiology and Intensive Care Medicine, Technical University Dresden, Fetscherstraße 74, 01307, Dresden, Germany.
  • Ullrich R; Department of Anaesthesia, Critical Care and Pain Medicince, Medical University of Vienna, Währinger Gürtel 18-20 / 9i, 1090, Vienna, Austria.
  • Marx G; Department of Intensive Care and Intermediate Care, University Hospital RWTH Aachen, Pauwelsstr.30, 52074, Aachen, Germany. gmarx@ukaachen.de.
Trials ; 20(1): 156, 2019 Mar 04.
Article em En | MEDLINE | ID: mdl-30832742
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 1_ASSA2030 / 4_TD / 6_ODS3_enfermedades_notrasmisibles Base de dados: MEDLINE Assunto principal: Peritonite / Imunoglobulina A / Imunoglobulina G / Imunoglobulina M / Imunoglobulinas Intravenosas / Sepse / Medicina de Precisão / Imunoterapia Tipo de estudo: Clinical_trials / Diagnostic_studies / Guideline / Observational_studies / Prognostic_studies / Risk_factors_studies Aspecto: Patient_preference Limite: Humans País/Região como assunto: Europa Idioma: En Revista: Trials Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 1_ASSA2030 / 4_TD / 6_ODS3_enfermedades_notrasmisibles Base de dados: MEDLINE Assunto principal: Peritonite / Imunoglobulina A / Imunoglobulina G / Imunoglobulina M / Imunoglobulinas Intravenosas / Sepse / Medicina de Precisão / Imunoterapia Tipo de estudo: Clinical_trials / Diagnostic_studies / Guideline / Observational_studies / Prognostic_studies / Risk_factors_studies Aspecto: Patient_preference Limite: Humans País/Região como assunto: Europa Idioma: En Revista: Trials Ano de publicação: 2019 Tipo de documento: Article