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TAS-121, A Selective Mutant EGFR Inhibitor, Shows Activity Against Tumors Expressing Various EGFR Mutations Including T790M and Uncommon Mutations G719X.
Ito, Kimihiro; Nishio, Makoto; Kato, Masanori; Murakami, Haruyasu; Aoyagi, Yoshimi; Ohe, Yuichiro; Okayama, Takashige; Hashimoto, Akihiro; Ohsawa, Hirokazu; Tanaka, Gotaro; Nonoshita, Katsumasa; Ito, Satoru; Matsuo, Kenichi; Miyadera, Kazutaka.
Afiliação
  • Ito K; Discovery and Preclinical Research Division, Taiho Pharmaceutical Co., Ltd., Tsukuba, Ibaraki, Japan.
  • Nishio M; Department of Thoracic Medical Oncology, The Cancer Institute Hospital of Japanese Foundation for Cancer Research, Tokyo, Japan.
  • Kato M; Discovery and Preclinical Research Division, Taiho Pharmaceutical Co., Ltd., Tsukuba, Ibaraki, Japan.
  • Murakami H; Division of Thoracic Oncology, Shizuoka Cancer Center, Shizuoka, Japan.
  • Aoyagi Y; Discovery and Preclinical Research Division, Taiho Pharmaceutical Co., Ltd., Tsukuba, Ibaraki, Japan.
  • Ohe Y; Department of Thoracic Oncology, National Cancer Center Hospital, Tokyo, Japan.
  • Okayama T; Discovery and Preclinical Research Division, Taiho Pharmaceutical Co., Ltd., Tsukuba, Ibaraki, Japan.
  • Hashimoto A; Discovery and Preclinical Research Division, Taiho Pharmaceutical Co., Ltd., Tsukuba, Ibaraki, Japan.
  • Ohsawa H; Discovery and Preclinical Research Division, Taiho Pharmaceutical Co., Ltd., Tsukuba, Ibaraki, Japan.
  • Tanaka G; Discovery and Preclinical Research Division, Taiho Pharmaceutical Co., Ltd., Tsukuba, Ibaraki, Japan.
  • Nonoshita K; Discovery and Preclinical Research Division, Taiho Pharmaceutical Co., Ltd., Tsukuba, Ibaraki, Japan.
  • Ito S; Discovery and Preclinical Research Division, Taiho Pharmaceutical Co., Ltd., Tsukuba, Ibaraki, Japan.
  • Matsuo K; Discovery and Preclinical Research Division, Taiho Pharmaceutical Co., Ltd., Tsukuba, Ibaraki, Japan.
  • Miyadera K; Discovery and Preclinical Research Division, Taiho Pharmaceutical Co., Ltd., Tsukuba, Ibaraki, Japan. k-miyadera@taiho.co.jp.
Mol Cancer Ther ; 18(5): 920-928, 2019 05.
Article em En | MEDLINE | ID: mdl-30872380
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirimidinas / Quinolinas / Carcinoma Pulmonar de Células não Pequenas / Inibidores de Proteínas Quinases / Proliferação de Células Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Mol Cancer Ther Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirimidinas / Quinolinas / Carcinoma Pulmonar de Células não Pequenas / Inibidores de Proteínas Quinases / Proliferação de Células Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Mol Cancer Ther Ano de publicação: 2019 Tipo de documento: Article