Ointment of Ximenes americana promotes acceleration of wound healing in rats1.
Acta Cir Bras
; 34(3): e201900307, 2019 Mar 18.
Article
em En
| MEDLINE
| ID: mdl-30892393
ABSTRACT
PURPOSE:
To evaluate the healing potential of the Ximenia americana hydroalcoholic extract in 10% cream in excisional wound models in rats.METHODS:
Sixty male adults Wistar rats were submitted to skin and subcutaneous tissue surgery in the right and left thoracic regions, divided into three experimental groups Standard submitted to treatment with only the base vehicle, Treated wounds treated with hydroalcoholic extract of X. americana applied on 10%, Lanette base and Control, untreated wounds. The treatment was performed daily and the wounds evaluated microscopically by the quantification of fibroblasts, collagen fibers and blood vessels.RESULTS:
The histomorphometric analysis showed a significant increase in the number of fibroblasts, collagen fibers and blood vessels in the treated group.CONCLUSION:
The topical action of the cream based on Ximenia americana shows angiogenic effects and improves the replacement of collagen, suggesting its use for the development of herbal remedy in the treatment of cutaneous wound healing.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Cicatrização
/
Extratos Vegetais
/
Olacaceae
Limite:
Animals
Idioma:
En
Revista:
Acta Cir Bras
Ano de publicação:
2019
Tipo de documento:
Article