Synthesis and Bioconjugation of Thiol-Reactive Reagents for the Creation of Site-Selectively Modified Immunoconjugates.

Davydova, Maria; Dewaele Le Roi, Guillaume; Adumeau, Pierre; Zeglis, Brian M

Davydova, Maria; Dewaele Le Roi, Guillaume; Adumeau, Pierre; Zeglis, Brian M.

Afiliação

Davydova M; Department of Chemistry, Hunter College of the City University of New York.
Dewaele Le Roi G; Department of Chemistry, Hunter College of the City University of New York; Ph.D. Program in Chemistry, Graduate Center of the City University of New York.
Adumeau P; Department of Chemistry, Hunter College of the City University of New York.
Zeglis BM; Department of Chemistry, Hunter College of the City University of New York; Ph.D. Program in Chemistry, Graduate Center of the City University of New York; Department of Radiology, Memorial Sloan Kettering Cancer Center; Department of Radiology, Weill Cornell Medical College; bz102@hunter.cuny.edu.

J Vis Exp ; (145)2019 03 06.

Article em En | MEDLINE | ID: mdl-30907883

Assuntos

Imunoconjugados/metabolismo; Reagentes de Sulfidrila/síntese química; Animais; Humanos; Maleimidas/química; Camundongos; Reagentes de Sulfidrila/química; Trastuzumab/farmacologia

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Reagentes de Sulfidrila / Imunoconjugados Tipo de estudo: Guideline Limite: Animals / Humans Idioma: En Revista: J Vis Exp Ano de publicação: 2019 Tipo de documento: Article

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