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Immune signature drives leukemia escape and relapse after hematopoietic cell transplantation.
Toffalori, Cristina; Zito, Laura; Gambacorta, Valentina; Riba, Michela; Oliveira, Giacomo; Bucci, Gabriele; Barcella, Matteo; Spinelli, Orietta; Greco, Raffaella; Crucitti, Lara; Cieri, Nicoletta; Noviello, Maddalena; Manfredi, Francesco; Montaldo, Elisa; Ostuni, Renato; Naldini, Matteo M; Gentner, Bernhard; Waterhouse, Miguel; Zeiser, Robert; Finke, Jurgen; Hanoun, Maher; Beelen, Dietrich W; Gojo, Ivana; Luznik, Leo; Onozawa, Masahiro; Teshima, Takanori; Devillier, Raynier; Blaise, Didier; Halkes, Constantijn J M; Griffioen, Marieke; Carrabba, Matteo G; Bernardi, Massimo; Peccatori, Jacopo; Barlassina, Cristina; Stupka, Elia; Lazarevic, Dejan; Tonon, Giovanni; Rambaldi, Alessandro; Cittaro, Davide; Bonini, Chiara; Fleischhauer, Katharina; Ciceri, Fabio; Vago, Luca.
Afiliação
  • Toffalori C; Unit of Immunogenetics, Leukemia Genomics and Immunobiology, Division of Immunology, Transplantation and Infectious Disease, IRCCS San Raffaele Scientific Institute, Milano, Italy.
  • Zito L; Unit of Immunogenetics, Leukemia Genomics and Immunobiology, Division of Immunology, Transplantation and Infectious Disease, IRCCS San Raffaele Scientific Institute, Milano, Italy.
  • Gambacorta V; Unit of Immunogenetics, Leukemia Genomics and Immunobiology, Division of Immunology, Transplantation and Infectious Disease, IRCCS San Raffaele Scientific Institute, Milano, Italy.
  • Riba M; Unit of Senescence in Stem Cell Aging, Differentiation and Cancer, San Raffaele Telethon Institute for Gene Therapy, IRCCS San Raffaele Scientific Institute, Milano, Italy.
  • Oliveira G; Center for Translational Genomics and Bioinformatics, IRCCS San Raffaele Scientific Institute, Milano, Italy.
  • Bucci G; Unit of Immunogenetics, Leukemia Genomics and Immunobiology, Division of Immunology, Transplantation and Infectious Disease, IRCCS San Raffaele Scientific Institute, Milano, Italy.
  • Barcella M; Experimental Hematology Unit, Division of Immunology, Transplantation and Infectious Disease, IRCCS San Raffaele Scientific Institute, Milano, Italy.
  • Spinelli O; Dana-Farber Cancer Institute, Boston, MA, USA.
  • Greco R; Unit of Immunogenetics, Leukemia Genomics and Immunobiology, Division of Immunology, Transplantation and Infectious Disease, IRCCS San Raffaele Scientific Institute, Milano, Italy.
  • Crucitti L; Center for Translational Genomics and Bioinformatics, IRCCS San Raffaele Scientific Institute, Milano, Italy.
  • Cieri N; Genomic and Bioinformatics Unit, Department of Health Sciences, University of Milano, Milano, Italy.
  • Noviello M; Hematology and Bone Marrow Transplant Unit, ASST Papa Giovanni XXIII, Bergamo, Italy.
  • Manfredi F; Unit of Hematology and Bone Marrow Transplantation, IRCCS San Raffaele Scientific Institute, Milano, Italy.
  • Montaldo E; Unit of Hematology and Bone Marrow Transplantation, IRCCS San Raffaele Scientific Institute, Milano, Italy.
  • Ostuni R; University of Milano, Milano, Italy.
  • Naldini MM; Experimental Hematology Unit, Division of Immunology, Transplantation and Infectious Disease, IRCCS San Raffaele Scientific Institute, Milano, Italy.
  • Gentner B; Unit of Hematology and Bone Marrow Transplantation, IRCCS San Raffaele Scientific Institute, Milano, Italy.
  • Waterhouse M; University of Milano, Milano, Italy.
  • Zeiser R; Experimental Hematology Unit, Division of Immunology, Transplantation and Infectious Disease, IRCCS San Raffaele Scientific Institute, Milano, Italy.
  • Finke J; Experimental Hematology Unit, Division of Immunology, Transplantation and Infectious Disease, IRCCS San Raffaele Scientific Institute, Milano, Italy.
  • Hanoun M; Genomics of the Innate Immune System Unit, San Raffaele Telethon Institute for Gene Therapy, IRCCS San Raffaele Scientific Institute, Milano, Italy.
  • Beelen DW; Genomics of the Innate Immune System Unit, San Raffaele Telethon Institute for Gene Therapy, IRCCS San Raffaele Scientific Institute, Milano, Italy.
  • Gojo I; Translational Stem Cell and Leukemia Unit, San Raffaele Telethon Institute for Gene Therapy, IRCCS San Raffaele Scientific Institute, Milano, Italy.
  • Luznik L; Unit of Hematology and Bone Marrow Transplantation, IRCCS San Raffaele Scientific Institute, Milano, Italy.
  • Onozawa M; Translational Stem Cell and Leukemia Unit, San Raffaele Telethon Institute for Gene Therapy, IRCCS San Raffaele Scientific Institute, Milano, Italy.
  • Teshima T; Department of Hematology, Oncology and Stem Cell Transplantation, Universitätsklinikum Freiburg, Freiburg, Germany.
  • Devillier R; Department of Hematology, Oncology and Stem Cell Transplantation, Universitätsklinikum Freiburg, Freiburg, Germany.
  • Blaise D; Department of Hematology, Oncology and Stem Cell Transplantation, Universitätsklinikum Freiburg, Freiburg, Germany.
  • Halkes CJM; Department of Bone Marrow Transplantation, Universitätsklinikum Essen, Essen, Germany.
  • Griffioen M; Department of Bone Marrow Transplantation, Universitätsklinikum Essen, Essen, Germany.
  • Carrabba MG; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • Bernardi M; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • Peccatori J; Department of Hematology, Hokkaido University Faculty of Medicine, Graduate School of Medicine, Sapporo, Japan.
  • Barlassina C; Department of Hematology, Hokkaido University Faculty of Medicine, Graduate School of Medicine, Sapporo, Japan.
  • Stupka E; Department of Haematology, Institut Paoli Calmettes, Marseille, France.
  • Lazarevic D; Department of Haematology, Institut Paoli Calmettes, Marseille, France.
  • Tonon G; Department of Hematology, Leiden University Medical Center, Leiden, The Netherlands.
  • Rambaldi A; Department of Hematology, Leiden University Medical Center, Leiden, The Netherlands.
  • Cittaro D; Unit of Hematology and Bone Marrow Transplantation, IRCCS San Raffaele Scientific Institute, Milano, Italy.
  • Bonini C; Unit of Hematology and Bone Marrow Transplantation, IRCCS San Raffaele Scientific Institute, Milano, Italy.
  • Fleischhauer K; Unit of Hematology and Bone Marrow Transplantation, IRCCS San Raffaele Scientific Institute, Milano, Italy.
  • Ciceri F; Genomic and Bioinformatics Unit, Department of Health Sciences, University of Milano, Milano, Italy.
  • Vago L; Center for Translational Genomics and Bioinformatics, IRCCS San Raffaele Scientific Institute, Milano, Italy.
Nat Med ; 25(4): 603-611, 2019 04.
Article em En | MEDLINE | ID: mdl-30911134
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucemia Mieloide Aguda / Transplante de Células-Tronco Hematopoéticas / Perfilação da Expressão Gênica Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Nat Med Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucemia Mieloide Aguda / Transplante de Células-Tronco Hematopoéticas / Perfilação da Expressão Gênica Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Nat Med Ano de publicação: 2019 Tipo de documento: Article