Leukocyte telomere length is not affected by long-term occupational exposure to nano metal oxides.
Ind Health
; 57(6): 741-744, 2019 Nov 29.
Article
em En
| MEDLINE
| ID: mdl-30918138
ABSTRACT
The aim of this study was to ascertain whether long-term occupational exposure to nanoparticles would affect relative leukocyte telomere length (LrTL). We analysed occupational exposure to size-resolved aerosol particles, with special emphasis on nanoparticles at two workshops i/ the production of nanocomposites containing metal oxides; ii/ laboratory to test experimental exposure of nano-CuO to rodents. Thirty five exposed researchers (age 39.5 ± 12.6â
yr; exposure duration 6.0 ± 3.7â
yr) and 43 controls (40.4 ± 10.5â
yr) were examined. LrTL did not significantly (p=0.14) differ between the exposed researchers (0.92 ± 0.13) and controls (0.86 ± 0.15). In addition, no significant correlation (r=-0.22, p=0.22) was detected between the duration of occupational exposure and LrTL. The results remained non-significant after multiple adjustments for age, sex and smoking status. Our pilot results suggest that relative leukocyte telomere length is not affected by occupational exposure to nanoparticles.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Contexto em Saúde:
2_ODS3
Base de dados:
MEDLINE
Assunto principal:
Pesquisadores
/
Exposição Ocupacional
/
Nanopartículas Metálicas
/
Encurtamento do Telômero
Limite:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
País/Região como assunto:
Europa
Idioma:
En
Revista:
Ind Health
Ano de publicação:
2019
Tipo de documento:
Article