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PI3K Inhibition Activates SGK1 via a Feedback Loop to Promote Chromatin-Based Regulation of ER-Dependent Gene Expression.
Toska, Eneda; Castel, Pau; Chhangawala, Sagar; Arruabarrena-Aristorena, Amaia; Chan, Carmen; Hristidis, Vasilis C; Cocco, Emiliano; Sallaku, Mirna; Xu, Guotai; Park, Jane; Minuesa, Gerard; Shifman, Sophie G; Socci, Nicholas D; Koche, Richard; Leslie, Christina S; Scaltriti, Maurizio; Baselga, José.
Afiliação
  • Toska E; Human Oncology and Pathogenesis Program (HOPP), Memorial Sloan Kettering Cancer Center, 1275 York Avenue, Box 20, New York, NY 10065, USA. Electronic address: toskae@mskcc.org.
  • Castel P; Human Oncology and Pathogenesis Program (HOPP), Memorial Sloan Kettering Cancer Center, 1275 York Avenue, Box 20, New York, NY 10065, USA; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, 1450 3rd Street, San Francisco, CA 94158, USA.
  • Chhangawala S; Computational Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Arruabarrena-Aristorena A; Human Oncology and Pathogenesis Program (HOPP), Memorial Sloan Kettering Cancer Center, 1275 York Avenue, Box 20, New York, NY 10065, USA.
  • Chan C; Human Oncology and Pathogenesis Program (HOPP), Memorial Sloan Kettering Cancer Center, 1275 York Avenue, Box 20, New York, NY 10065, USA.
  • Hristidis VC; Human Oncology and Pathogenesis Program (HOPP), Memorial Sloan Kettering Cancer Center, 1275 York Avenue, Box 20, New York, NY 10065, USA.
  • Cocco E; Human Oncology and Pathogenesis Program (HOPP), Memorial Sloan Kettering Cancer Center, 1275 York Avenue, Box 20, New York, NY 10065, USA.
  • Sallaku M; Human Oncology and Pathogenesis Program (HOPP), Memorial Sloan Kettering Cancer Center, 1275 York Avenue, Box 20, New York, NY 10065, USA.
  • Xu G; Human Oncology and Pathogenesis Program (HOPP), Memorial Sloan Kettering Cancer Center, 1275 York Avenue, Box 20, New York, NY 10065, USA.
  • Park J; Center of Epigenetics Research, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Minuesa G; Molecular Pharmacology Program, Memorial Sloan Kettering Institute, New York, NY 10065, USA.
  • Shifman SG; Human Oncology and Pathogenesis Program (HOPP), Memorial Sloan Kettering Cancer Center, 1275 York Avenue, Box 20, New York, NY 10065, USA.
  • Socci ND; Bioinformatics Core, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Koche R; Center of Epigenetics Research, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Leslie CS; Computational Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Scaltriti M; Human Oncology and Pathogenesis Program (HOPP), Memorial Sloan Kettering Cancer Center, 1275 York Avenue, Box 20, New York, NY 10065, USA; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Baselga J; Human Oncology and Pathogenesis Program (HOPP), Memorial Sloan Kettering Cancer Center, 1275 York Avenue, Box 20, New York, NY 10065, USA; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Research & Development Oncology, AstraZeneca Pharmaceuticals, Gaithe
Cell Rep ; 27(1): 294-306.e5, 2019 04 02.
Article em En | MEDLINE | ID: mdl-30943409
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptores de Estrogênio / Proteínas Serina-Treonina Quinases / Proteínas Imediatamente Precoces / Fosfatidilinositol 3-Quinases / Retroalimentação Fisiológica / Montagem e Desmontagem da Cromatina Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Cell Rep Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptores de Estrogênio / Proteínas Serina-Treonina Quinases / Proteínas Imediatamente Precoces / Fosfatidilinositol 3-Quinases / Retroalimentação Fisiológica / Montagem e Desmontagem da Cromatina Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Cell Rep Ano de publicação: 2019 Tipo de documento: Article