Contributions of the C-terminal domain to poly(A)-specific ribonuclease (PARN) stability and self-association.

He, Guang-Jun; Yan, Yong-Bin

He, Guang-Jun; Yan, Yong-Bin.

Afiliação

He GJ; State Key Laboratory of Membrane Biology, School of Life Sciences, Tsinghua University, Beijing, 100084, China.
Yan YB; State Key Laboratory of Membrane Biology, School of Life Sciences, Tsinghua University, Beijing, 100084, China.

Biochem Biophys Rep ; 18: 100626, 2019 Jul.

Article em En | MEDLINE | ID: mdl-30949591

Palavras-chave

CD, circular dichroism; CTD, C-terminal domain; Deadenylase; Enzyme thermal aggregation; Enzyme thermal stability; IPTG, isopropyl-1-thio-ß-d-galactopyranoside; Intrinsically disordered domain; PARN, poly(A)-specific ribonuclease; Poly(A)-Specific ribonuclease (PARN); Self-association; p46, PARN with the removal of RRM and CTD (residues 1446); p60, PARN with the removal of CTD (residues 1520); p74, the full-length PARN

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Risk_factors_studies Idioma: En Revista: Biochem Biophys Rep Ano de publicação: 2019 Tipo de documento: Article

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