Effects of Processing on a Sustained Release Formulation Prepared by Twin-Screw Dry Granulation.

Ye, Xingyou; Kallakunta, Venkataraman; Kim, Dong Wuk; Patil, Hemlata; Tiwari, Roshan V; Upadhye, Sampada B; Vladyka, Ron S; Repka, Michael A

Ye, Xingyou; Kallakunta, Venkataraman; Kim, Dong Wuk; Patil, Hemlata; Tiwari, Roshan V; Upadhye, Sampada B; Vladyka, Ron S; Repka, Michael A.

Afiliação

Ye X; Department of Pharmaceutics and Drug Delivery, School of Pharmacy, The University of Mississippi, University, Mississippi 38677.
Kallakunta V; Department of Pharmaceutics and Drug Delivery, School of Pharmacy, The University of Mississippi, University, Mississippi 38677.
Kim DW; Department of Pharmaceutics and Drug Delivery, School of Pharmacy, The University of Mississippi, University, Mississippi 38677.
Patil H; Department of Pharmaceutics and Drug Delivery, School of Pharmacy, The University of Mississippi, University, Mississippi 38677.
Tiwari RV; Department of Pharmaceutics and Drug Delivery, School of Pharmacy, The University of Mississippi, University, Mississippi 38677.
Upadhye SB; Catalent Pharma Solutions, 14 Schoolhouse Road, Somerset, New Jersey 08873.
Vladyka RS; Catalent Pharma Solutions, 14 Schoolhouse Road, Somerset, New Jersey 08873.
Repka MA; Department of Pharmaceutics and Drug Delivery, School of Pharmacy, The University of Mississippi, University, Mississippi 38677; Pii Center for Pharmaceutical Technology, The University of Mississippi, University, Mississippi 38677. Electronic address: marepka@olemiss.edu.

J Pharm Sci ; 108(9): 2895-2904, 2019 09.

Article em En | MEDLINE | ID: mdl-30965041

Assuntos

Dessecação/métodos; Composição de Medicamentos/métodos; Excipientes/química; Teofilina/química; Química Farmacêutica/instrumentação; Química Farmacêutica/métodos; Preparações de Ação Retardada/química; Preparações de Ação Retardada/farmacocinética; Dessecação/instrumentação; Composição de Medicamentos/instrumentação; Liberação Controlada de Fármacos; Estudos de Viabilidade; Tamanho da Partícula; Solubilidade; Comprimidos; Temperatura; Resistência à Tração; Teofilina/farmacocinética

Palavras-chave

design of experiment; dissolution time; flow property; particle size; theophylline; twin-screw dry granulation

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Teofilina / Dessecação / Composição de Medicamentos / Excipientes Idioma: En Revista: J Pharm Sci Ano de publicação: 2019 Tipo de documento: Article

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