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Novel Antimycobacterial Compounds Suppress NAD Biogenesis by Targeting a Unique Pocket of NaMN Adenylyltransferase.
Osterman, Andrei L; Rodionova, Irina; Li, Xiaoqing; Sergienko, Eduard; Ma, Chen-Ting; Catanzaro, Antonino; Pettigrove, Mark E; Reed, Robert W; Gupta, Rashmi; Rohde, Kyle H; Korotkov, Konstantin V; Sorci, Leonardo.
Afiliação
  • Osterman AL; Sanford Burnham Prebys Medical Discovery Institute , La Jolla , California 92037 , United States.
  • Rodionova I; Sanford Burnham Prebys Medical Discovery Institute , La Jolla , California 92037 , United States.
  • Li X; Sanford Burnham Prebys Medical Discovery Institute , La Jolla , California 92037 , United States.
  • Sergienko E; NCI Designated Cancer Center , Sanford Burnham Prebys Medical Discovery Institute , La Jolla , California 92037 , United States.
  • Ma CT; NCI Designated Cancer Center , Sanford Burnham Prebys Medical Discovery Institute , La Jolla , California 92037 , United States.
  • Catanzaro A; Department of Medicine , University of California San Diego , La Jolla , California 92093 , United States.
  • Pettigrove ME; Department of Medicine , University of California San Diego , La Jolla , California 92093 , United States.
  • Reed RW; Department of Molecular and Cellular Biochemistry, College of Medicine , University of Kentucky , Lexington , Kentucky 40508 , United States.
  • Gupta R; Division of Immunity and Pathogenesis , Burnett School of Biomedical Sciences, College of Medicine, University of Central Florida , Orlando , Florida 32827 , United States.
  • Rohde KH; Division of Immunity and Pathogenesis , Burnett School of Biomedical Sciences, College of Medicine, University of Central Florida , Orlando , Florida 32827 , United States.
  • Korotkov KV; Department of Molecular and Cellular Biochemistry, College of Medicine , University of Kentucky , Lexington , Kentucky 40508 , United States.
  • Sorci L; Department of Materials, Environmental Sciences and Urban Planning, Division of Bioinformatics and Biochemistry , Polytechnic University of Marche , Ancona 60131 , Italy.
ACS Chem Biol ; 14(5): 949-958, 2019 05 17.
Article em En | MEDLINE | ID: mdl-30969758
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 3_ND Base de dados: MEDLINE Assunto principal: Mycobacterium tuberculosis / NAD / Nicotinamida-Nucleotídeo Adenililtransferase / Antituberculosos Idioma: En Revista: ACS Chem Biol Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 3_ND Base de dados: MEDLINE Assunto principal: Mycobacterium tuberculosis / NAD / Nicotinamida-Nucleotídeo Adenililtransferase / Antituberculosos Idioma: En Revista: ACS Chem Biol Ano de publicação: 2019 Tipo de documento: Article