Hospital effluent: A reservoir for carbapenemase-producing Enterobacterales?
Sci Total Environ
; 672: 618-624, 2019 Jul 01.
Article
em En
| MEDLINE
| ID: mdl-30974353
ABSTRACT
Antimicrobial resistance is a major public health concern. Carbapenemase-producing Enterobacterales (CPE) represent a significant health threat as some strains are resistant to almost all available antibiotics. The aim of this research was to examine hospital effluent and municipal wastewater in an urban area in Ireland for CPE. Samples of hospital effluent (nâ¯=â¯5), municipal wastewater before (nâ¯=â¯5) and after (nâ¯=â¯4) the hospital effluent stream joined the municipal wastewater stream were collected over a nine-week period (May-June 2017). All samples were examined for CPE by direct plating onto Brilliance CRE agar. Isolates were selected for susceptibility testing to 15 antimicrobial agents in accordance with EUCAST criteria. Where relevant, isolates were tested for carbapenemase-encoding genes by real-time PCR. CPE were detected in five samples of hospital effluent, one sample of pre-hospital wastewater and three samples of post-hospital wastewater. Our findings suggest hospital effluent is a major contributor to CPE in municipal wastewater. Monitoring of hospital effluent for CPE could have important applications in detection and risk management of unrecognised dissemination of CPE in both the healthcare setting and the environment.
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Texto completo:
1
Coleções:
01-internacional
Contexto em Saúde:
3_ND
Base de dados:
MEDLINE
Assunto principal:
Proteínas de Bactérias
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Microbiologia da Água
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Poluentes da Água
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Beta-Lactamases
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Enterobacteriaceae
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Águas Residuárias
Idioma:
En
Revista:
Sci Total Environ
Ano de publicação:
2019
Tipo de documento:
Article