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A novel CRISPR-engineered prostate cancer cell line defines the AR-V transcriptome and identifies PARP inhibitor sensitivities.
Kounatidou, Evangelia; Nakjang, Sirintra; McCracken, Stuart R C; Dehm, Scott M; Robson, Craig N; Jones, Dominic; Gaughan, Luke.
Afiliação
  • Kounatidou E; Northern Institute for Cancer Research, Newcastle University, Paul O'Gorman Building, Framlington Place, Newcastle Upon Tyne, NE2 4HH, UK.
  • Nakjang S; Northern Institute for Cancer Research, Newcastle University, Paul O'Gorman Building, Framlington Place, Newcastle Upon Tyne, NE2 4HH, UK.
  • McCracken SRC; Northern Institute for Cancer Research, Newcastle University, Paul O'Gorman Building, Framlington Place, Newcastle Upon Tyne, NE2 4HH, UK.
  • Dehm SM; University of Minnesota, Department of Laboratory Medicine and Pathology, MMC 806 Mayo, 420 Delaware, Minneapolis, MN 55455, USA.
  • Robson CN; Northern Institute for Cancer Research, Newcastle University, Paul O'Gorman Building, Framlington Place, Newcastle Upon Tyne, NE2 4HH, UK.
  • Jones D; Northern Institute for Cancer Research, Newcastle University, Paul O'Gorman Building, Framlington Place, Newcastle Upon Tyne, NE2 4HH, UK.
  • Gaughan L; Northern Institute for Cancer Research, Newcastle University, Paul O'Gorman Building, Framlington Place, Newcastle Upon Tyne, NE2 4HH, UK.
Nucleic Acids Res ; 47(11): 5634-5647, 2019 06 20.
Article em En | MEDLINE | ID: mdl-31006810
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 6_ODS3_enfermedades_notrasmisibles Base de dados: MEDLINE Assunto principal: Neoplasias da Próstata / Receptores Androgênicos / Sistemas CRISPR-Cas / Inibidores de Poli(ADP-Ribose) Polimerases Tipo de estudo: Diagnostic_studies Limite: Humans / Male Idioma: En Revista: Nucleic Acids Res Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 6_ODS3_enfermedades_notrasmisibles Base de dados: MEDLINE Assunto principal: Neoplasias da Próstata / Receptores Androgênicos / Sistemas CRISPR-Cas / Inibidores de Poli(ADP-Ribose) Polimerases Tipo de estudo: Diagnostic_studies Limite: Humans / Male Idioma: En Revista: Nucleic Acids Res Ano de publicação: 2019 Tipo de documento: Article