Feralgine™ a New Approach for Iron Deficiency Anemia in Celiac Patients.
Nutrients
; 11(4)2019 Apr 20.
Article
em En
| MEDLINE
| ID: mdl-31009990
ABSTRACT
BACKGROUND:
Celiac disease (CD) is an immunologically-mediated disorder characterized by duodenal mucosa villi atrophy. Iron absorption is usually reduced in celiac patients making every kind of oral iron treatment unhelpful because of malasorption. Feralgine™ is a new product that has been demonstrated to be more bioavailable. As such, the aim of our study was to evaluate the absorption of Feralgine™ in adult patients with CD.METHODS:
Twenty-six adults affected by Iron Deficiency Anemia (IDA), of which 14 were also affected by CD and 12 were not affected by CD, were enrolled. An oral iron absorption test (OIAT) was performed in each patient by administrating Feralgine™, and serum iron was evaluated at baseline (T0) and after 2 h (T1) from the oral iron ingestion.RESULTS:
The OIAT was well tolerated in all patients, and, surprisingly, an equivalent statistically significant improvement in serum iron occurred in the two groups of patients (IDA plus CD T0 = 28.21 µg/dL vs. T1 = 94.14 µg/dL p = 0.004 and IDA without CD T0 = 34.91 µg/dL vs. T1 = 118.83 µg/dL, p = 0.0003).CONCLUSIONS:
These results demonstrated the high absorption of Feralgine™ in celiac patients, confirming our previous data obtained with Ferrous Bysglicinate in children with CD.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Compostos Ferrosos
/
Doença Celíaca
/
Anemia Ferropriva
/
Alginatos
/
Deficiências de Ferro
/
Glicina
/
Absorção Intestinal
Limite:
Adult
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
Nutrients
Ano de publicação:
2019
Tipo de documento:
Article