An Overview of PulseNet USA Databases.
Foodborne Pathog Dis
; 16(7): 457-462, 2019 07.
Article
em En
| MEDLINE
| ID: mdl-31066584
ABSTRACT
PulseNet USA is the molecular surveillance network for foodborne disease in the United States. The network consists of state and local public health laboratories, as well as food regulatory agencies, that follow PulseNet's standardized protocols to perform pulsed-field gel electrophoresis (PFGE) and whole genome sequencing (WGS) and analyze the results using standardized software. The raw sequences are uploaded to the GenomeTrakr or PulseNet bioprojects at the National Center for Biotechnology Information. The PFGE patterns and analyzed sequence data are uploaded in real time with associated demographic data to the PulseNet national databases managed at the Centers for Disease Control and Prevention. The PulseNet databases are organism specific and provide a central storage location for molecular and demographic data related to an isolate. Sequences are compared in the databases, thereby facilitating the rapid detection of clusters of foodborne diseases that may represent widespread outbreaks. WGS genotyping data, for example, antibiotic resistance and virulence profiles, are also uploaded in real time to the PulseNet databases to improve food safety surveillance activities.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Contexto em Saúde:
1_ASSA2030
/
3_ND
Base de dados:
MEDLINE
Assunto principal:
Saúde Pública
/
Surtos de Doenças
/
Bases de Dados como Assunto
/
Doenças Transmitidas por Alimentos
/
Laboratórios
Aspecto:
Determinantes_sociais_saude
Limite:
Humans
País/Região como assunto:
America do norte
Idioma:
En
Revista:
Foodborne Pathog Dis
Ano de publicação:
2019
Tipo de documento:
Article