Prognosis of Early-stage Part-solid and Pure-solid Lung Adenocarcinomas.

ABSTRACT

BACKGROUND/AIM: In the new TNM classification (8th edition) of lung cancer, T category is defined based on the solid component size; therefore, part solid type (PST) with and solid type (ST) without ground glass opacity (GGO) are categorized as same T value according to their solid component sizes. However, differences between these tumors have not been clarified. Patients and Methods The study included 274 pStage I lung adenocarcinoma patients who had undergone surgery at our Institution from 2003 to 2012. Their tumors were classified as pure GGO, PST, and ST. After propensity score matching for solid component size, we compared prognoses between PST and ST. RESULTS: The same percentage was noted for PST and ST tumors (119/274; 43.4%). After propensity score matching, the disease-free survival (DFS) was significantly worse in ST than PST (5-year DFS 69.2% versus 88.7%; p=0.0241). CONCLUSION: Prognoses of PST and ST adenocarcinomas differ even when their solid component sizes are the same.