How Gastrin-Releasing Peptide Opens the Spinal Gate for Itch.

Pagani, Martina; Albisetti, Gioele W; Sivakumar, Nandhini; Wildner, Hendrik; Santello, Mirko; Johannssen, Helge C; Zeilhofer, Hanns Ulrich

Pagani, Martina; Albisetti, Gioele W; Sivakumar, Nandhini; Wildner, Hendrik; Santello, Mirko; Johannssen, Helge C; Zeilhofer, Hanns Ulrich.

Afiliação

Pagani M; Institute of Pharmacology and Toxicology, University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland; Neuroscience Center Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland.
Albisetti GW; Institute of Pharmacology and Toxicology, University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland; Neuroscience Center Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland.
Sivakumar N; Institute of Pharmacology and Toxicology, University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland.
Wildner H; Institute of Pharmacology and Toxicology, University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland.
Santello M; Institute of Pharmacology and Toxicology, University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland; Neuroscience Center Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland.
Johannssen HC; Institute of Pharmacology and Toxicology, University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland.
Zeilhofer HU; Institute of Pharmacology and Toxicology, University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland; Neuroscience Center Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland; Drug Discovery Network Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland; Institute of Pharmaceuti

Neuron ; 103(1): 102-117.e5, 2019 07 03.

Article em En | MEDLINE | ID: mdl-31103358

Assuntos

Peptídeo Liberador de Gastrina/genética; Prurido/fisiopatologia; Potenciais de Ação/fisiologia; Animais; Comportamento Animal; Feminino; Imuno-Histoquímica; Masculino; Camundongos; Camundongos Transgênicos; Neurônios; Optogenética; Bloqueadores dos Canais de Potássio/farmacologia; Prurido/genética; Prurido/psicologia; Receptores da Bombesina/antagonistas & inibidores; Receptores da Bombesina/genética; Receptores de Glutamato/fisiologia; Receptores Pré-Sinápticos/metabolismo; Medula Espinal/citologia

Palavras-chave

GRP receptor; co-transmission; dorsal horn; interneuron; neuropeptide; optogenetics; pruritus; sensory processing; synaptic transmission; volume transmission

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Prurido / Peptídeo Liberador de Gastrina Limite: Animals Idioma: En Revista: Neuron Ano de publicação: 2019 Tipo de documento: Article

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