Adipose-derived stromal cell secretome reduces TNF&#945;-induced hypertrophy and catabolic markers in primary human articular chondrocytes.

Niada, Stefania; Giannasi, Chiara; Gomarasca, Marta; Stanco, Deborah; Casati, Sara; Brini, Anna Teresa

Adipose-derived stromal cell secretome reduces TNFα-induced hypertrophy and catabolic markers in primary human articular chondrocytes.

Niada, Stefania; Giannasi, Chiara; Gomarasca, Marta; Stanco, Deborah; Casati, Sara; Brini, Anna Teresa.

Afiliação

Niada S; Laboratory of Biotechnological Applications, IRCCS Istituto Ortopedico Galeazzi, Italy. Electronic address: stefania.niada@grupposandonato.it.
Giannasi C; Laboratory of Biotechnological Applications, IRCCS Istituto Ortopedico Galeazzi, Italy. Electronic address: chiara.giannasi@grupposandonato.it.
Gomarasca M; Laboratory of Biotechnological Applications, IRCCS Istituto Ortopedico Galeazzi, Italy. Electronic address: marta.gomarasca@grupposandonato.it.
Stanco D; Department of Mechanical and Aerospace Engineering, Politecnico di Torino, Turin, Italy.
Casati S; Department of Biomedical, Surgical and Dental Sciences, University of Milan, Italy. Electronic address: sara.casati@unimi.it.
Brini AT; Laboratory of Biotechnological Applications, IRCCS Istituto Ortopedico Galeazzi, Italy; Department of Biomedical, Surgical and Dental Sciences, University of Milan, Italy. Electronic address: anna.brini@unimi.it.

Stem Cell Res ; 38: 101463, 2019 07.

Article em En | MEDLINE | ID: mdl-31108390

Assuntos

Tecido Adiposo/metabolismo; Cartilagem Articular/metabolismo; Condrócitos/metabolismo; Células-Tronco Mesenquimais/metabolismo; Osteoartrite/metabolismo; Fator de Necrose Tumoral alfa/farmacologia; Tecido Adiposo/patologia; Adulto; Cartilagem Articular/patologia; Condrócitos/patologia; Feminino; Humanos; Hipertrofia; Masculino; Células-Tronco Mesenquimais/patologia; Pessoa de Meia-Idade; Osteoartrite/patologia

Palavras-chave

Adipose-derived stromal cells; Chondrocytes; Hypertrophy; MMPs; Secretome; TIMPs

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Osteoartrite / Cartilagem Articular / Tecido Adiposo / Fator de Necrose Tumoral alfa / Condrócitos / Células-Tronco Mesenquimais Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Stem Cell Res Ano de publicação: 2019 Tipo de documento: Article

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