Novel mutant mouse line emphasizes the importance of protein kinase C theta for CD4<sup>+</sup> T lymphocyte activation.

Siegmund, Kerstin; Thuille, Nikolaus; Posch, Nina; Fresser, Friedrich; Leitges, Michael; Baier, Gottfried

Novel mutant mouse line emphasizes the importance of protein kinase C theta for CD4⁺ T lymphocyte activation.

Siegmund, Kerstin; Thuille, Nikolaus; Posch, Nina; Fresser, Friedrich; Leitges, Michael; Baier, Gottfried.

Afiliação

Siegmund K; Department for Pharmacology and Genetics, Medical University Innsbruck, Division of Translational Cell Genetics, Peter Mayr Str. 1a, A-6020, Innsbruck, Austria. Kerstin.Siegmund@i-med.ac.at.
Thuille N; Department for Pharmacology and Genetics, Medical University Innsbruck, Division of Translational Cell Genetics, Peter Mayr Str. 1a, A-6020, Innsbruck, Austria.
Posch N; Department for Pharmacology and Genetics, Medical University Innsbruck, Division of Translational Cell Genetics, Peter Mayr Str. 1a, A-6020, Innsbruck, Austria.
Fresser F; Department for Pharmacology and Genetics, Medical University Innsbruck, Division of Translational Cell Genetics, Peter Mayr Str. 1a, A-6020, Innsbruck, Austria.
Leitges M; Biotechnology Center of Oslo, Oslo, Norway.
Baier G; Department for Pharmacology and Genetics, Medical University Innsbruck, Division of Translational Cell Genetics, Peter Mayr Str. 1a, A-6020, Innsbruck, Austria. Gottfried.Baier@i-med.ac.at.

Cell Commun Signal ; 17(1): 56, 2019 05 28.

Article em En | MEDLINE | ID: mdl-31138259

Assuntos

Linfócitos T CD4-Positivos/imunologia; Ativação Linfocitária; Mutação; Proteína Quinase C-theta/genética; Animais; Células HEK293; Humanos; Células Jurkat; Camundongos; Camundongos Endogâmicos C57BL; Fenótipo; Proteína Quinase C-theta/metabolismo

Palavras-chave

Interleukin- 2 (IL-2); Protein kinase C theta (PKCÎ¸); Regulatory T cell development; T lymphocyte signaling and activation

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ativação Linfocitária / Linfócitos T CD4-Positivos / Proteína Quinase C-theta / Mutação Limite: Animals / Humans Idioma: En Revista: Cell Commun Signal Ano de publicação: 2019 Tipo de documento: Article

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