Ion-production efficiency of a singly charged ion source developed toward a 11C irradiation facility for cancer therapy.
Rev Sci Instrum
; 90(5): 053303, 2019 May.
Article
em En
| MEDLINE
| ID: mdl-31153246
ABSTRACT
The ion-production efficiency of a newly developed singly charged ion source (SCIS) has been investigated to discuss the possibility of it being used in an isotope separation on-line system that provides 11C ions for heavy-ion cancer therapy with simultaneous verification of the irradiation field using positron emission tomography. The SCIS uses a low-energy hollow electron beam to produce singly charged carbon ions efficiently. To deliver sufficient 11C ions to the treatment room from a limited amount of 11C molecules, which are produced from a boron compound target and proton-beam irradiation via the 11B(p,n)11C reaction, the SCIS must have high ion-production efficiency. To realize this high efficiency, the SCIS was designed using a three-dimensional particle-in-cell code in previous work. With the fabricated SCIS, we performed experiments to measure the efficiency of producing CO2 + ions from nonradioactive 12CO2 molecules and C+ ions from nonradioactive 12CH4 molecules. We found that the SCIS achieved efficiencies of εC+ =4×10-3 (0.4%) for C+ production and εCO2 + =0.107 (10.7%) for CO2 + production.
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1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Radioquímica
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Radioisótopos de Carbono
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Radioterapia com Íons Pesados
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Neoplasias
Idioma:
En
Revista:
Rev Sci Instrum
Ano de publicação:
2019
Tipo de documento:
Article