The local properties of bold signal fluctuations at rest monitor inhibitory control training in adolescents.
Dev Cogn Neurosci
; 38: 100664, 2019 08.
Article
em En
| MEDLINE
| ID: mdl-31158801
ABSTRACT
Inhibitory control (IC) plays a critical role in cognitive and socio-emotional development. Short-term IC training improves IC abilities in children and adults. Surprisingly, few studies have investigated the IC training effect during adolescence, a developmental period characterized by high neuroplasticity and the protracted development of IC abilities. We investigated behavioural and functional brain changes induced by a 5-week computerized and adaptive IC training in adolescents. We focused on the IC training effects on the local properties of functional Magnetic Resonance Imaging (fMRI) signal fluctuations at rest (i.e., Regional Homogeneity [ReHo] and fractional Amplitude of Low Frequency Fluctuations [fALFF]). Sixty adolescents were randomly assigned to either an IC or an active control training group. In the pre- and post-training sessions, cognitive ('Cool') and emotional ('Hot') IC abilities were assessed using the Colour-Word and Emotional Stroop tasks. We found that ReHo and fALFF signals in IC areas (IFG, ACC, Striatum) were associated with IC efficiency at baseline. This association was different for Cool and Hot IC. Analyses also revealed that ReHo and fALFF signals were sensitive markers to detect and monitor changes after IC training, while behavioural data did not, suggesting that brain functional changes at rest precede behavioural changes following training.
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Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Encéfalo
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Comportamento do Adolescente
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Teste de Stroop
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Inibição Psicológica
Tipo de estudo:
Clinical_trials
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Observational_studies
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Risk_factors_studies
Limite:
Adolescent
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Adult
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Child
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Female
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Humans
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Male
Idioma:
En
Revista:
Dev Cogn Neurosci
Ano de publicação:
2019
Tipo de documento:
Article