[Ulcerative colitis caused by oral gold therapy in rheumatoid arthritis]. / Ulzerierende Kolitis unter oraler Goldtherapie bei rheumatoider Arthritis.
Z Rheumatol
; 46(4): 201-4, 1987.
Article
em De
| MEDLINE
| ID: mdl-3118590
ABSTRACT
We report on a 39-year-old male patient suffering from seropositive rheumatoid arthritis who developed severe colitis during oral gold (Auranofin) therapy. So far, two further cases of colitis during oral, and 28 cases of enterocolitis during parenteral chrysotherapy have been described. The pathomechanism has not been identified. Symptomatic therapy was applied, under which our patient recovered from intestinal discomfort in a few weeks. In differential diagnosis gold induced colitis has to be distinguished both from loose stools occurring during oral gold therapy, most probably caused by an inhibition of NA+K+ ATPase, and from colitis induced by concomitant application of nonsteroidal anti-inflammatory drugs.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Artrite Reumatoide
/
Colite Ulcerativa
/
Aurotioglucose
/
Ouro
Tipo de estudo:
Prognostic_studies
Limite:
Adult
/
Humans
/
Male
Idioma:
De
Revista:
Z Rheumatol
Ano de publicação:
1987
Tipo de documento:
Article