Dense Bodies of a gH/gL/UL128/UL130/UL131 Pentamer-Repaired Towne Strain of Human Cytomegalovirus Induce an Enhanced Neutralizing Antibody Response.

Lehmann, Caroline; Falk, Jessica Julia; Büscher, Nicole; Penner, Inessa; Zimmermann, Christine; Gogesch, Patricia; Sinzger, Christian; Plachter, Bodo

Lehmann, Caroline; Falk, Jessica Julia; Büscher, Nicole; Penner, Inessa; Zimmermann, Christine; Gogesch, Patricia; Sinzger, Christian; Plachter, Bodo.

Afiliação

Lehmann C; Institute for Virology, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.
Falk JJ; Institute for Virology, Ulm University Medical Center, Ulm, Germany.
Büscher N; Institute for Virology, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.
Penner I; Institute for Virology, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.
Zimmermann C; Institute for Virology, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.
Gogesch P; Institute for Virology, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.
Sinzger C; Institute for Virology, Ulm University Medical Center, Ulm, Germany.
Plachter B; Institute for Virology, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany plachter@uni-mainz.de.

J Virol ; 93(17)2019 09 01.

Article em En | MEDLINE | ID: mdl-31189713

Assuntos

Anticorpos Neutralizantes/metabolismo; Infecções por Citomegalovirus/imunologia; Citomegalovirus/imunologia; Proteínas do Envelope Viral/imunologia; Animais; Células Cultivadas; Vacinas contra Citomegalovirus/imunologia; Prepúcio do Pênis/citologia; Prepúcio do Pênis/virologia; Células Endoteliais da Veia Umbilical Humana; Humanos; Masculino; Glicoproteínas de Membrana/imunologia; Camundongos; Complexos Multiproteicos/imunologia; Coelhos

Palavras-chave

cytomegalovirus; dense bodies; gH/gL/UL128-131; neutralizing antibodies; pentamer; vaccine

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas do Envelope Viral / Infecções por Citomegalovirus / Citomegalovirus / Anticorpos Neutralizantes Limite: Animals / Humans / Male Idioma: En Revista: J Virol Ano de publicação: 2019 Tipo de documento: Article

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