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De-escalation of tyrosine kinase inhibitor therapy before complete treatment discontinuation in patients with chronic myeloid leukaemia (DESTINY): a non-randomised, phase 2 trial.
Clark, Richard E; Polydoros, Fotios; Apperley, Jane F; Milojkovic, Dragana; Rothwell, Katherine; Pocock, Christopher; Byrne, Jennifer; de Lavallade, Hugues; Osborne, Wendy; Robinson, Lisa; O'Brien, Stephen G; Read, Lucy; Foroni, Letizia; Copland, Mhairi.
Afiliação
  • Clark RE; Department of Haematology, Royal Liverpool University Hospital, Liverpool, UK. Electronic address: clarkre@liverpool.ac.uk.
  • Polydoros F; Liverpool Cancer Trials Unit, University of Liverpool, Liverpool, UK.
  • Apperley JF; Department of Haematology, Hammersmith Hospital, London, UK.
  • Milojkovic D; Department of Haematology, Hammersmith Hospital, London, UK.
  • Rothwell K; Department of Haematology, St James University Hospital, Leeds, UK.
  • Pocock C; Department of Haematology, East Kent Hospitals, Canterbury, UK.
  • Byrne J; Department of Haematology, City Hospital, Nottingham, UK.
  • de Lavallade H; Department of Haematology, King's College Hospital, London, UK.
  • Osborne W; Department of Haematology, Freeman Hospital, Newcastle-on-Tyne, UK.
  • Robinson L; Department of Haematology, Wye Vale NHS Trust, Hereford, UK.
  • O'Brien SG; Department of Haematology, Freeman Hospital, Newcastle-on-Tyne, UK.
  • Read L; Liverpool Cancer Trials Unit, University of Liverpool, Liverpool, UK.
  • Foroni L; Department of Haematology, Hammersmith Hospital, London, UK.
  • Copland M; Paul O'Gorman Leukaemia Research Centre, University of Glasgow, Glasgow, UK.
Lancet Haematol ; 6(7): e375-e383, 2019 Jul.
Article em En | MEDLINE | ID: mdl-31201085
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucemia Mielogênica Crônica BCR-ABL Positiva / Inibidores de Proteínas Quinases Tipo de estudo: Clinical_trials / Guideline / Prognostic_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Lancet Haematol Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucemia Mielogênica Crônica BCR-ABL Positiva / Inibidores de Proteínas Quinases Tipo de estudo: Clinical_trials / Guideline / Prognostic_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Lancet Haematol Ano de publicação: 2019 Tipo de documento: Article