Unfolded protein response is involved in geniposide-regulating glucose-stimulated insulin secretion in INS-1 cells.

Hao, Yanan; Shen, Shenli; Yin, Fei; Zhang, Yonglan; Liu, Jianhui

Hao, Yanan; Shen, Shenli; Yin, Fei; Zhang, Yonglan; Liu, Jianhui.

Afiliação

Hao Y; Chongqing Key Laboratory of Medicinal Chemistry and Molecular Pharmacology, Chongqing University of Technology, Chongqing, China.
Shen S; Chongqing Key Laboratory of Medicinal Chemistry and Molecular Pharmacology, Chongqing University of Technology, Chongqing, China.
Yin F; Chongqing Key Laboratory of Medicinal Chemistry and Molecular Pharmacology, Chongqing University of Technology, Chongqing, China.
Zhang Y; Chongqing Key Laboratory of Medicinal Chemistry and Molecular Pharmacology, Chongqing University of Technology, Chongqing, China.
Liu J; Chongqing Key Laboratory of Medicinal Chemistry and Molecular Pharmacology, Chongqing University of Technology, Chongqing, China.

Cell Biochem Funct ; 37(5): 368-376, 2019 Jul.

Article em En | MEDLINE | ID: mdl-31215684

Assuntos

Glucose/metabolismo; Secreção de Insulina/efeitos dos fármacos; Células Secretoras de Insulina/efeitos dos fármacos; Iridoides/farmacologia; Resposta a Proteínas não Dobradas/fisiologia; Animais; Linhagem Celular; Células Secretoras de Insulina/metabolismo; Ratos

Palavras-chave

endoplasmic reticulum (ER); geniposide; inositol-requiring enzyme 1 (IRE1); protein kinase RNA (PKR)-like ER kinase (PERK); thioredoxin interacting protein (Txnip); unfolded protein response (UPR)

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Iridoides / Células Secretoras de Insulina / Resposta a Proteínas não Dobradas / Secreção de Insulina / Glucose Limite: Animals Idioma: En Revista: Cell Biochem Funct Ano de publicação: 2019 Tipo de documento: Article

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