Human-induced pluripotent stem cell-derived cardiomyocytes have limited I<sub>Ks</sub> for repolarization reserve as revealed by specific KCNQ1/KCNE1 blocker.

Zeng, Haoyu; Wang, Jixin; Clouse, Holly; Lagrutta, Armando; Sannajust, Frederick

Human-induced pluripotent stem cell-derived cardiomyocytes have limited I_Ks for repolarization reserve as revealed by specific KCNQ1/KCNE1 blocker.

Zeng, Haoyu; Wang, Jixin; Clouse, Holly; Lagrutta, Armando; Sannajust, Frederick.

Afiliação

Zeng H; Merck & Co., Inc., Safety and Exploratory Pharmacology, West Point, PA, USA.
Wang J; Merck & Co., Inc., Safety and Exploratory Pharmacology, West Point, PA, USA.
Clouse H; Merck & Co., Inc., Safety and Exploratory Pharmacology, West Point, PA, USA.
Lagrutta A; Merck & Co., Inc., Safety and Exploratory Pharmacology, West Point, PA, USA.
Sannajust F; Merck & Co., Inc., Safety and Exploratory Pharmacology, West Point, PA, USA.

JRSM Cardiovasc Dis ; 8: 2048004019854919, 2019.

Article em En | MEDLINE | ID: mdl-31217965

Palavras-chave

Stem cell; cardiomyocyte

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: JRSM Cardiovasc Dis Ano de publicação: 2019 Tipo de documento: Article

Texto completo

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XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: JRSM Cardiovasc Dis Ano de publicação: 2019 Tipo de documento: Article