Effect of Linagliptin on the Ratio of Apoptosis Regulators in the Model of Non-Alcoholic Fatty Liver Disease in db/db Mice.

Michurina, S V; Cherepanova, M A; Ishchenko, I Yu; Arkhipov, S A; Klimontov, V V; Zav'yalov, E L

Michurina, S V; Cherepanova, M A; Ishchenko, I Yu; Arkhipov, S A; Klimontov, V V; Zav'yalov, E L.

Afiliação

Michurina SV; Research Institute of Clinical and Experimental Lymphology, Affiliated Branch of Federal Research Center Institute of Cytology and Genetics, Novosibirsk, Russia. s.michurina@ngs.ru.
Cherepanova MA; Research Institute of Clinical and Experimental Lymphology, Affiliated Branch of Federal Research Center Institute of Cytology and Genetics, Novosibirsk, Russia.
Ishchenko IY; Research Institute of Clinical and Experimental Lymphology, Affiliated Branch of Federal Research Center Institute of Cytology and Genetics, Novosibirsk, Russia.
Arkhipov SA; Research Institute of Clinical and Experimental Lymphology, Affiliated Branch of Federal Research Center Institute of Cytology and Genetics, Novosibirsk, Russia.
Klimontov VV; Research Institute of Clinical and Experimental Lymphology, Affiliated Branch of Federal Research Center Institute of Cytology and Genetics, Novosibirsk, Russia.
Zav'yalov EL; Federal Research Center Institute for Cytology and Genetics, Siberian Division of the Russian Academy of Sciences, Novosibirsk, Russia.

Bull Exp Biol Med ; 167(2): 210-214, 2019 Jun.

Article em En | MEDLINE | ID: mdl-31236880

Assuntos

Linagliptina/uso terapêutico; Hepatopatia Gordurosa não Alcoólica/tratamento farmacológico; Hepatopatia Gordurosa não Alcoólica/metabolismo; Animais; Apoptose/efeitos dos fármacos; Diabetes Mellitus Tipo 2; Inibidores da Dipeptidil Peptidase IV/uso terapêutico; Fígado; Masculino; Camundongos; Obesidade/tratamento farmacológico; Obesidade/metabolismo; Proteínas Proto-Oncogênicas c-bcl-2/metabolismo; Proteína de Morte Celular Associada a bcl/metabolismo

Palavras-chave

apoptosis; db/db mice; linagliptin; liver; type 2 diabetes mellitus

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Hepatopatia Gordurosa não Alcoólica / Linagliptina Limite: Animals Idioma: En Revista: Bull Exp Biol Med Ano de publicação: 2019 Tipo de documento: Article

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