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The E3 ligase TRIM56 is a host restriction factor of Zika virus and depends on its RNA-binding activity but not miRNA regulation, for antiviral function.
Yang, Darong; Li, Nan L; Wei, Dahai; Liu, Baoming; Guo, Fang; Elbahesh, Husni; Zhang, Yunzhi; Zhou, Zhi; Chen, Guo-Yun; Li, Kui.
Afiliação
  • Yang D; Department of Microbiology, Immunology and Biochemistry, University of Tennessee Health Science Center, Memphis, TN, United States of America.
  • Li NL; Children's Foundation Research Institute at Le Bonheur Children's Hospital, Department of Pediatrics, University of Tennessee Health Science Center, Memphis, TN, United States of America.
  • Wei D; Department of Microbiology, Immunology and Biochemistry, University of Tennessee Health Science Center, Memphis, TN, United States of America.
  • Liu B; Department of Microbiology, Immunology and Biochemistry, University of Tennessee Health Science Center, Memphis, TN, United States of America.
  • Guo F; Department of Microbiology, Immunology and Biochemistry, University of Tennessee Health Science Center, Memphis, TN, United States of America.
  • Elbahesh H; Baruch S. Blumberg Institute, Doylestown, PA, United States of America.
  • Zhang Y; Department of Microbiology, Immunology and Biochemistry, University of Tennessee Health Science Center, Memphis, TN, United States of America.
  • Zhou Z; Department of Microbiology, Immunology and Biochemistry, University of Tennessee Health Science Center, Memphis, TN, United States of America.
  • Chen GY; Department of Infectious Diseases, the Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
  • Li K; Department of Infectious Diseases, the Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
PLoS Negl Trop Dis ; 13(6): e0007537, 2019 06.
Article em En | MEDLINE | ID: mdl-31251739

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: RNA Viral / Proteínas de Ligação a RNA / MicroRNAs / Ubiquitina-Proteína Ligases / Zika virus / Proteínas com Motivo Tripartido / Fatores Imunológicos Limite: Humans Idioma: En Revista: PLoS Negl Trop Dis Ano de publicação: 2019 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: RNA Viral / Proteínas de Ligação a RNA / MicroRNAs / Ubiquitina-Proteína Ligases / Zika virus / Proteínas com Motivo Tripartido / Fatores Imunológicos Limite: Humans Idioma: En Revista: PLoS Negl Trop Dis Ano de publicação: 2019 Tipo de documento: Article