Integrated Computational Analysis Highlights unique miRNA Signatures in the Subventricular Zone and Striatum of GM2 Gangliosidosis Animal Models.

Morena, Francesco; Oikonomou, Vasileios; Argentati, Chiara; Bazzucchi, Martina; Emiliani, Carla; Gritti, Angela; Martino, Sabata

Morena, Francesco; Oikonomou, Vasileios; Argentati, Chiara; Bazzucchi, Martina; Emiliani, Carla; Gritti, Angela; Martino, Sabata.

Afiliação

Morena F; Department of Chemistry, Biology and Biotechnology, Biochemical and Biotechnological Sciences, University of Perugia, Perugia 06126, Italy. francesco.morena@unipg.it.
Oikonomou V; Department of Chemistry, Biology and Biotechnology, Biochemical and Biotechnological Sciences, University of Perugia, Perugia 06126, Italy.
Argentati C; Department of Chemistry, Biology and Biotechnology, Biochemical and Biotechnological Sciences, University of Perugia, Perugia 06126, Italy.
Bazzucchi M; Department of Chemistry, Biology and Biotechnology, Biochemical and Biotechnological Sciences, University of Perugia, Perugia 06126, Italy.
Emiliani C; Department of Chemistry, Biology and Biotechnology, Biochemical and Biotechnological Sciences, University of Perugia, Perugia 06126, Italy.
Gritti A; San Raffaele Telethon Institute for Gene Therapy, IRCCS San Raffaele Scientific Institute, Milan 20132, Italy.
Martino S; Department of Chemistry, Biology and Biotechnology, Biochemical and Biotechnological Sciences, University of Perugia, Perugia 06126, Italy. sabata.martino@unipg.it.

Int J Mol Sci ; 20(13)2019 Jun 28.

Article em En | MEDLINE | ID: mdl-31261761

Assuntos

Corpo Estriado/metabolismo; Gangliosidoses GM2/genética; Redes Reguladoras de Genes; Ventrículos Laterais/metabolismo; MicroRNAs/genética; Transcriptoma; Animais; Gangliosidoses GM2/metabolismo; Metabolismo dos Lipídeos/genética; Camundongos; Camundongos Endogâmicos C57BL; Neurogênese/genética

Palavras-chave

Hexosaminidase; epigenetics; lysosomal storage disorders; striatum; subventricular zone

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Corpo Estriado / Ventrículos Laterais / Gangliosidoses GM2 / MicroRNAs / Redes Reguladoras de Genes / Transcriptoma Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Int J Mol Sci Ano de publicação: 2019 Tipo de documento: Article

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