Rational use of the fluoroquinolones.
S Afr Med J
; 109(6): 378-381, 2019 May 31.
Article
em En
| MEDLINE
| ID: mdl-31266554
ABSTRACT
The systemic fluoroquinolones (FQs) have recently been reported to be associated with significant side-effects in susceptible individuals. This has prompted the Food and Drug Administration (FDA) in the USA and the European Medicines Agency (EMA) to issue warnings regarding their use. The FQs should not be used for common bacterial infections, such as urinary tract infections, travellers' diarrhoea and upper and lower respiratory tract infections, unless it is not possible to use another oral agent. There are situations, however, in which these agents are not only effective, but their benefit outweighs the risk. These include the management of conditions such as acute prostatitis, typhoid fever, prosthetic joint infections, multidrug-resistant tuberculosis, certain hospital-acquired infections and situations where the organism is susceptible to FQs, which could then be administered orally. Alternatively, the patient would have to be admitted to hospital for parenteral therapy.
Texto completo:
1
Coleções:
01-internacional
Contexto em Saúde:
2_ODS3
/
3_ND
Base de dados:
MEDLINE
Assunto principal:
Prostatite
/
Febre Tifoide
/
Infecção Hospitalar
/
Infecções Relacionadas à Prótese
/
Tuberculose Resistente a Múltiplos Medicamentos
/
Fluoroquinolonas
Tipo de estudo:
Etiology_studies
Limite:
Humans
/
Male
Idioma:
En
Revista:
S Afr Med J
Ano de publicação:
2019
Tipo de documento:
Article