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Molecular tuning of farnesoid X receptor partial agonism.
Merk, Daniel; Sreeramulu, Sridhar; Kudlinzki, Denis; Saxena, Krishna; Linhard, Verena; Gande, Santosh L; Hiller, Fabian; Lamers, Christina; Nilsson, Ewa; Aagaard, Anna; Wissler, Lisa; Dekker, Niek; Bamberg, Krister; Schubert-Zsilavecz, Manfred; Schwalbe, Harald.
Afiliação
  • Merk D; Institute of Pharmaceutical Chemistry, Goethe University, Frankfurt, 60348, Germany. merk@pharmchem.uni-frankfurt.de.
  • Sreeramulu S; Center for Biomolecular Magnetic Resonance (BMRZ), Institute for Organic Chemistry and Chemical Biology, Goethe University, Frankfurt, 60438, Germany.
  • Kudlinzki D; Center for Biomolecular Magnetic Resonance (BMRZ), Institute for Organic Chemistry and Chemical Biology, Goethe University, Frankfurt, 60438, Germany.
  • Saxena K; German Cancer Consortium (DKTK), Heidelberg, 69120, Germany.
  • Linhard V; German Cancer Research Center (DKFZ), Heidelberg, 69120, Germany.
  • Gande SL; Center for Biomolecular Magnetic Resonance (BMRZ), Institute for Organic Chemistry and Chemical Biology, Goethe University, Frankfurt, 60438, Germany.
  • Hiller F; German Cancer Consortium (DKTK), Heidelberg, 69120, Germany.
  • Lamers C; German Cancer Research Center (DKFZ), Heidelberg, 69120, Germany.
  • Nilsson E; Center for Biomolecular Magnetic Resonance (BMRZ), Institute for Organic Chemistry and Chemical Biology, Goethe University, Frankfurt, 60438, Germany.
  • Aagaard A; Center for Biomolecular Magnetic Resonance (BMRZ), Institute for Organic Chemistry and Chemical Biology, Goethe University, Frankfurt, 60438, Germany.
  • Wissler L; German Cancer Consortium (DKTK), Heidelberg, 69120, Germany.
  • Dekker N; German Cancer Research Center (DKFZ), Heidelberg, 69120, Germany.
  • Bamberg K; Center for Biomolecular Magnetic Resonance (BMRZ), Institute for Organic Chemistry and Chemical Biology, Goethe University, Frankfurt, 60438, Germany.
  • Schubert-Zsilavecz M; Institute of Pharmaceutical Chemistry, Goethe University, Frankfurt, 60348, Germany.
  • Schwalbe H; Innovative Medicines and Early Development Biotech Unit, AstraZeneca, Gothenburg, 43183, Sweden.
Nat Commun ; 10(1): 2915, 2019 07 02.
Article em En | MEDLINE | ID: mdl-31266946
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptores Citoplasmáticos e Nucleares Limite: Animals / Humans / Male Idioma: En Revista: Nat Commun Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptores Citoplasmáticos e Nucleares Limite: Animals / Humans / Male Idioma: En Revista: Nat Commun Ano de publicação: 2019 Tipo de documento: Article