Atherogenic index of plasma and its association with cardiovascular disease risk factors among postmenopausal rural women of Bangladesh.

ABSTRACT

OBJECTIVES: There is absolute lacking of evidences on atherogenic index of plasma (AIP) and its association with cardiovascular disease (CVD) risk factors among postmenopausal women of Bangladesh. This prompted us to investigate this association between AIP and CVD risk factors among postmenopausal women in a rural setting. METHODS: This cross-sectional study recruited 265 postmenopausal women aged 40-70 years who visited a primary health-care center of Bangladesh. We used modified STEP-wise approach for the Surveillance of Noncommunicable diseases risk factors questionnaire of the World Health Organization to collect data on sociodemographic and behavioral risk factors. Physical measurements were carried out following the method described in the 'noncommunicable disease risk factors survey Bangladesh 2010'. AIP was determined by the logarithmic transformation of triglyceride to high-density lipoprotein ratio, and association with CVD risk factors were examined by multiple linear regression analysis. RESULTS: Overall 35.5% respondents had a high risk level of AIP with a mean of 0.16 ± 0.25. After adjusting the confounders, CVD risk factors including duration of menopause (ß = 0.606, p = 0.043), waist-hip ratio (ß = 0.165, p = 0.003), 2-h plasma glucose (ß = 0.118, p = 0.04), total cholesterol (ß = 1.082, p < 0.001), low-density lipoprotein cholesterol (ß = -1.044, p < 0.001), and metabolic equivalent of tasks (ß = -0.171, p = 0.003) showed a significant association with AIP. CONCLUSION: High AIP and its significant association with CVD risk factors demand proper lifestyle intervention for postmenopausal women of Bangladesh.