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Triazole-Pyridine Dicarbonitrile Targets Phosphodiesterase 4 to Induce Cytotoxicity in Lung Carcinoma Cells.
Keerthy, Hosadurga K; Mohan, Surender; Bharathkumar, Hanumantharayappa; Rangappa, Shobith; Svensson, Fredrick; Bender, Andreas; Mohan, Chakrabhavi Dhananjaya; Rangappa, Kanchugarakoppal S; Bhatnagar, Rakesh.
Afiliação
  • Keerthy HK; Department of Chemistry, Center for Post Graduate Studies and Research, St. Agnes College, Bendur, Mangalore, 575002, India.
  • Mohan S; Center for Molecular Informatics, Department of Chemistry, University of Cambridge, Cambridge, CB2 1EW, United Kingdom.
  • Basappa; Laboratory of Molecular Biology and Genetic Engineering, School of Biotechnology, Jawaharlal Nehru University, New Delhi, 110067, India.
  • Bharathkumar H; Laboratory of Chemical Biology, Department of Chemistry, Bangalore University, Central College campus, Palace Road, Bangalore, 560001, India.
  • Rangappa S; Laboratory of Chemical Biology, Department of Studies in Organic Chemistry, University of Mysore, Manasagangotri, Mysore, 570006, India.
  • Svensson F; Laboratory of Chemical Biology, Department of Chemistry, Bangalore University, Central College campus, Palace Road, Bangalore, 560001, India.
  • Bender A; Adichunchanagiri Institute for Molecular Medicine, BG Nagara, 571448, Nagamangala Taluk, Mandya District, India.
  • Mohan CD; Center for Molecular Informatics, Department of Chemistry, University of Cambridge, Cambridge, CB2 1EW, United Kingdom.
  • Rangappa KS; Center for Molecular Informatics, Department of Chemistry, University of Cambridge, Cambridge, CB2 1EW, United Kingdom.
  • Bhatnagar R; Department of Studies in Molecular Biology, University of Mysore, Manasagangotri, Mysore, 570006, India.
Chem Biodivers ; 16(9): e1900234, 2019 Sep.
Article em En | MEDLINE | ID: mdl-31287204
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Piridinas / Triazóis / Nucleotídeo Cíclico Fosfodiesterase do Tipo 4 / Inibidores da Fosfodiesterase 4 / Neoplasias Pulmonares / Antineoplásicos / Nitrilas Limite: Humans Idioma: En Revista: Chem Biodivers Ano de publicação: 2019 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Piridinas / Triazóis / Nucleotídeo Cíclico Fosfodiesterase do Tipo 4 / Inibidores da Fosfodiesterase 4 / Neoplasias Pulmonares / Antineoplásicos / Nitrilas Limite: Humans Idioma: En Revista: Chem Biodivers Ano de publicação: 2019 Tipo de documento: Article