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Single cell analysis of autism patient with bi-allelic NRXN1-alpha deletion reveals skewed fate choice in neural progenitors and impaired neuronal functionality.
Lam, Matti; Moslem, Mohsen; Bryois, Julien; Pronk, Robin J; Uhlin, Elias; Ellström, Ivar Dehnisch; Laan, Loora; Olive, Jessica; Morse, Rebecca; Rönnholm, Harriet; Louhivuori, Lauri; Korol, Sergiy V; Dahl, Niklas; Uhlén, Per; Anderlid, Britt-Marie; Kele, Malin; Sullivan, Patrick F; Falk, Anna.
Afiliação
  • Lam M; Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden.
  • Moslem M; Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden.
  • Bryois J; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
  • Pronk RJ; Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden.
  • Uhlin E; Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden.
  • Ellström ID; Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.
  • Laan L; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.
  • Olive J; Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden.
  • Morse R; Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden.
  • Rönnholm H; Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden.
  • Louhivuori L; Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.
  • Korol SV; Department of Neuroscience, Uppsala University, Uppsala, Sweden.
  • Dahl N; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.
  • Uhlén P; Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.
  • Anderlid BM; Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.
  • Kele M; Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden.
  • Sullivan PF; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
  • Falk A; Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden. Electronic address: Anna.Falk@ki.se.
Exp Cell Res ; 383(1): 111469, 2019 10 01.
Article em En | MEDLINE | ID: mdl-31302032
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transtorno Autístico / Proteínas de Ligação ao Cálcio / Deleção de Genes / Moléculas de Adesão de Célula Nervosa / Células-Tronco Pluripotentes Induzidas / Células-Tronco Neurais / Análise de Célula Única / Proteínas do Tecido Nervoso Limite: Humans Idioma: En Revista: Exp Cell Res Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transtorno Autístico / Proteínas de Ligação ao Cálcio / Deleção de Genes / Moléculas de Adesão de Célula Nervosa / Células-Tronco Pluripotentes Induzidas / Células-Tronco Neurais / Análise de Célula Única / Proteínas do Tecido Nervoso Limite: Humans Idioma: En Revista: Exp Cell Res Ano de publicação: 2019 Tipo de documento: Article