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Sickle cell disease in anaemic children in a Sierra Leonean district hospital: a case series.
Italia, Maria B; Kirolos, Sandy.
Afiliação
  • Italia MB; Medical Department, Médecins Sans Frontières, Barcelona, Spain.
  • Kirolos S; Paediatric Department, Koinadugu Government Hospital, Kabala, Sierra Leone.
Oxf Med Case Reports ; 2019(7): omz061, 2019 Jul.
Article em En | MEDLINE | ID: mdl-31312461
Sickle cell disease (SCD) is the most common inherited haemoglobinopathy wordwide, with the highest prevalence in sub-Saharan Africa. Due to the lack of national strategies and scarcity of diagnostic tools in resource-limited settings, the disease may be significantly underdiagnosed. We carried out a 6-month retrospective review of paediatric admissions in a district hospital in northern Sierra Leone. Our aim was to identify patients with severe anaemia, defined as Hb < 7 g/dl, and further analyse the records of those tested for SCD. Of the 273 patients identified, only 24.5% had had an Emmel test, among which 34.3% were positive. Furthermore, only 17% of patients with a positive Emmel test were discharged on prophylactic antibiotics. Our study shows that increased awareness of SCD symptoms is required in high-burden areas without established screening programmes. In addition, the creation or strengthening of follow-up programmes for SCD patients is essential for disease control.

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies / Risk_factors_studies Idioma: En Revista: Oxf Med Case Reports Ano de publicação: 2019 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies / Risk_factors_studies Idioma: En Revista: Oxf Med Case Reports Ano de publicação: 2019 Tipo de documento: Article