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Propofol directly induces caspase-1-dependent macrophage pyroptosis through the NLRP3-ASC inflammasome.
Sun, Lingbin; Ma, Wei; Gao, Wenli; Xing, Yanmei; Chen, Lixin; Xia, Zhengyuan; Zhang, Zhongjun; Dai, Zhongliang.
Afiliação
  • Sun L; The Department of Anesthesiology, The Second Clinical Medical College (Shenzhen People's Hospital), Jinan University, No. 1017 Dongmen North Road, Shenzhen, People's Republic of China.
  • Ma W; Integrated Chinese and Western Medicine Postdoctoral Research Station, Jinan University, Shipai, Guangzhou, People's Republic of China.
  • Gao W; Translational Medicine Collaorative Innovation Center, The Second Clinical Medical College (Shenzhen People's Hospital), Jinan University, No. 1017 Dongmen North Road, Shenzhen, People's Republic of China.
  • Xing Y; The Department of Anesthesiology, The Second Clinical Medical College (Shenzhen People's Hospital), Jinan University, No. 1017 Dongmen North Road, Shenzhen, People's Republic of China.
  • Chen L; The Department of Anesthesiology, The Second Clinical Medical College (Shenzhen People's Hospital), Jinan University, No. 1017 Dongmen North Road, Shenzhen, People's Republic of China.
  • Xia Z; Department of Pharmacology, Medical College, Jinan University, Shipai, Guangzhou, People's Republic of China.
  • Zhang Z; Department of Anesthesiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, People's Republic of China.
  • Dai Z; The Department of Anesthesiology, The Second Clinical Medical College (Shenzhen People's Hospital), Jinan University, No. 1017 Dongmen North Road, Shenzhen, People's Republic of China.
Cell Death Dis ; 10(8): 542, 2019 07 17.
Article em En | MEDLINE | ID: mdl-31316052
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Propofol / Caspase 1 / Proteínas Adaptadoras de Sinalização CARD / Piroptose / Proteína 3 que Contém Domínio de Pirina da Família NLR / Macrófagos Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Revista: Cell Death Dis Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Propofol / Caspase 1 / Proteínas Adaptadoras de Sinalização CARD / Piroptose / Proteína 3 que Contém Domínio de Pirina da Família NLR / Macrófagos Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Revista: Cell Death Dis Ano de publicação: 2019 Tipo de documento: Article