Topiramate pharmacokinetics in neonates undergoing therapeutic hypothermia and proposal of an optimised dosing schedule.

Marques, María Remedios; Garcia-Robles, Ana; Usach, Iris; Vento, Maximo; Poveda, José Luis; Peris, José Esteban; Mangas-Sanjuan, Victor

Marques, María Remedios; Garcia-Robles, Ana; Usach, Iris; Vento, Maximo; Poveda, José Luis; Peris, José Esteban; Mangas-Sanjuan, Victor.

Afiliação

Marques MR; Department of Pharmacy Services, University and Polytechnic Hospital La Fe, Valencia, Spain.
Garcia-Robles A; Division of Neonatology, University and Polytechnic Hospital La Fe, Valencia, Spain.
Usach I; Department of Pharmacy and Pharmaceutical Technology and Parasitology, University of Valencia, Valencia, Spain.
Vento M; Division of Neonatology, University and Polytechnic Hospital La Fe, Valencia, Spain.
Poveda JL; Department of Pharmacy Services, University and Polytechnic Hospital La Fe, Valencia, Spain.
Peris JE; Department of Pharmacy and Pharmaceutical Technology and Parasitology, University of Valencia, Valencia, Spain.
Mangas-Sanjuan V; Department of Pharmacy and Pharmaceutical Technology and Parasitology, University of Valencia, Valencia, Spain.

Acta Paediatr ; 109(2): 300-308, 2020 02.

Article em En | MEDLINE | ID: mdl-31336401

Assuntos

Hipotermia Induzida; Hipóxia-Isquemia Encefálica; Humanos; Hipóxia-Isquemia Encefálica/terapia; Recém-Nascido; Convulsões; Topiramato

Palavras-chave

hypoxic ischaemic encephalopathy; neonates; population pharmacokinetics; therapeutic hypothermia; topiramate dosing

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Hipóxia-Isquemia Encefálica / Hipotermia Induzida Limite: Humans / Newborn Idioma: En Revista: Acta Paediatr Ano de publicação: 2020 Tipo de documento: Article

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