Cognitive improvement after carotid artery stenting in patients with symptomatic internal carotid artery near-occlusion.
J Neurol Sci
; 404: 86-90, 2019 Sep 15.
Article
em En
| MEDLINE
| ID: mdl-31352294
ABSTRACT
BACKGROUND AND PURPOSE:
To investigate the influence of carotid artery stenting (CAS) with embolic protection device (EPD) on the cognitive function of patients with near-occlusion of the cervical internal carotid artery (ICA).METHODS:
From February 2014 to December 2017, a total of 79 symptomatic patients were recruited in this study. Of these patients, 31 patients refused to receive CAS therapy. They were divided into the CAS group (48 patients) and the medical treatment group (31 patients). Montreal cognitive assessment (MoCA) instrument was used for the evaluation of cognitive function. The analyzed endpoints included cumulative 12â¯month incidence of ipsilateral ischemic cerebrovascular events and MoCA scores at 1â¯month and 12â¯months after treatment.RESULTS:
Cumulative 12â¯months incidence of ipsilateral ischemic cerebrovascular events was lower in patients who underwent CAS than in patients on medical treatment (Pâ¯<â¯0.05). In CAS group, the total MoCA score, scores of attention and delayed recall at months 1 and 12 increased when compared with those at baseline (Pâ¯<â¯0.05). In medical treatment group, the total MoCA score and attention score at month 12 decreased when compared with those at baseline (Pâ¯<â¯0.05). In CAS group, the total MoCA score, scores of line connection test, drawing clock, attention and delayed recall were improved at 1 and 12â¯months when compared with medical treatment at the same time points (Pâ¯<â¯0.05).CONCLUSIONS:
CAS with EPD not only decreases the risk of ipsilateral TIA and stroke but also may improve the cognitive function of symptomatic patients with ICA near-occlusion.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Artéria Carótida Interna
/
Estenose das Carótidas
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Cognição
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Disfunção Cognitiva
Tipo de estudo:
Diagnostic_studies
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Etiology_studies
Limite:
Aged
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Female
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Humans
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Male
Idioma:
En
Revista:
J Neurol Sci
Ano de publicação:
2019
Tipo de documento:
Article