The Genetic Duet of <i>BRAF</i> V600E and <i>TERT</i> Promoter Mutations Robustly Predicts Loss of Radioiodine Avidity in Recurrent Papillary Thyroid Cancer.

Liu, Jiajun; Liu, Rengyun; Shen, Xiaopei; Zhu, Guangwu; Li, Biao; Xing, Mingzhao

The Genetic Duet of BRAF V600E and TERT Promoter Mutations Robustly Predicts Loss of Radioiodine Avidity in Recurrent Papillary Thyroid Cancer.

Liu, Jiajun; Liu, Rengyun; Shen, Xiaopei; Zhu, Guangwu; Li, Biao; Xing, Mingzhao.

Afiliação

Liu J; Laboratory for Cellular and Molecular Thyroid Research, Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland; and.
Liu R; Department of Nuclear Medicine, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Shen X; Laboratory for Cellular and Molecular Thyroid Research, Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland; and.
Zhu G; Laboratory for Cellular and Molecular Thyroid Research, Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland; and.
Li B; Laboratory for Cellular and Molecular Thyroid Research, Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland; and.
Xing M; Department of Nuclear Medicine, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

J Nucl Med ; 61(2): 177-182, 2020 02.

Article em En | MEDLINE | ID: mdl-31375570

Assuntos

Radioisótopos do Iodo/uso terapêutico; Mutação; Regiões Promotoras Genéticas/genética; Proteínas Proto-Oncogênicas B-raf/genética; Telomerase/genética; Câncer Papilífero da Tireoide/genética; Câncer Papilífero da Tireoide/radioterapia; Adulto; Idoso; Estudos de Coortes; Feminino; Genótipo; Humanos; Masculino; Pessoa de Meia-Idade; Prognóstico; Recidiva; Câncer Papilífero da Tireoide/diagnóstico

Palavras-chave

BRAF V600E; TERT promoter mutation; radioiodine therapy; recurrence; thyroid cancer

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Regiões Promotoras Genéticas / Telomerase / Proteínas Proto-Oncogênicas B-raf / Câncer Papilífero da Tireoide / Radioisótopos do Iodo / Mutação Tipo de estudo: Diagnostic_studies / Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: J Nucl Med Ano de publicação: 2020 Tipo de documento: Article

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