Emerging Nonsteroid-Based Procedural Therapies for Alopecia Areata: A Systematic Review.
Dermatol Surg
; 45(12): 1484-1506, 2019 12.
Article
em En
| MEDLINE
| ID: mdl-31403534
ABSTRACT
BACKGROUND:
Alopecia areata (AA) is a common form of patchy, nonscarring hair loss. Although intralesional steroid injections are currently the mainstay procedural therapy for AA, other nonsteroid-based procedural therapies, including platelet-rich plasma (PRP), ultraviolet radiation (UVR), and laser-based modalities, are emerging as practical options.OBJECTIVE:
To systematically review nonsteroid-based procedural therapies for AA and recapitulate the available clinical data. MATERIALS ANDMETHODS:
A systematic review of the literature was performed searching PubMed/MEDLINE databases identifying studies investigating PRP, UVR, and laser-based modalities for AA treatment.RESULTS:
Literature search yielded 644 articles encompassing PRP, UVR, and laser treatment modalities for AA. Of the 644 articles, 46 met inclusion criteria. Although numerous reports demonstrate strong potential for PRP, UVR, and laser modalities in treating AA, high-quality evidence supporting their efficacy is still lacking.CONCLUSION:
There is an abundance of evidence for nonsteroid-based procedural therapies in the treatment of AA. Randomized control trials comparing these treatment options head-to-head should be performed to better understand the true efficacy of these treatments.
Texto completo:
1
Coleções:
01-internacional
Contexto em Saúde:
1_ASSA2030
Base de dados:
MEDLINE
Assunto principal:
Terapia Ultravioleta
/
Terapia com Luz de Baixa Intensidade
/
Alopecia em Áreas
/
Plasma Rico em Plaquetas
Tipo de estudo:
Clinical_trials
/
Prognostic_studies
/
Systematic_reviews
Limite:
Humans
Idioma:
En
Revista:
Dermatol Surg
Ano de publicação:
2019
Tipo de documento:
Article