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Adult and iPS-derived non-parenchymal cells regulate liver organoid development through differential modulation of Wnt and TGF-ß.
Goulart, Ernesto; de Caires-Junior, Luiz Carlos; Telles-Silva, Kayque Alves; Araujo, Bruno Henrique Silva; Kobayashi, Gerson S; Musso, Camila Manso; Assoni, Amanda Faria; Oliveira, Danyllo; Caldini, Elia; Gerstenhaber, Jonathan A; Raia, Silvano; Lelkes, Peter I; Zatz, Mayana.
Afiliação
  • Goulart E; Human Genome and Stem-Cell Research Center (HUG-CEL), Department of Genetics and Evolutionary Biology, Institute of Biosciences, University of São Paulo, São Paulo, SP, Brazil.
  • de Caires-Junior LC; Human Genome and Stem-Cell Research Center (HUG-CEL), Department of Genetics and Evolutionary Biology, Institute of Biosciences, University of São Paulo, São Paulo, SP, Brazil.
  • Telles-Silva KA; Human Genome and Stem-Cell Research Center (HUG-CEL), Department of Genetics and Evolutionary Biology, Institute of Biosciences, University of São Paulo, São Paulo, SP, Brazil.
  • Araujo BHS; Brazilian Biosciences National Laboratory (LNBio), Brazilian Center for Research in Energy and Materials (CNPEM), Campinas, SP, 13083-970, Brazil.
  • Kobayashi GS; Human Genome and Stem-Cell Research Center (HUG-CEL), Department of Genetics and Evolutionary Biology, Institute of Biosciences, University of São Paulo, São Paulo, SP, Brazil.
  • Musso CM; Human Genome and Stem-Cell Research Center (HUG-CEL), Department of Genetics and Evolutionary Biology, Institute of Biosciences, University of São Paulo, São Paulo, SP, Brazil.
  • Assoni AF; Human Genome and Stem-Cell Research Center (HUG-CEL), Department of Genetics and Evolutionary Biology, Institute of Biosciences, University of São Paulo, São Paulo, SP, Brazil.
  • Oliveira D; Human Genome and Stem-Cell Research Center (HUG-CEL), Department of Genetics and Evolutionary Biology, Institute of Biosciences, University of São Paulo, São Paulo, SP, Brazil.
  • Caldini E; Laboratory of Cellular Biology, Department of Pathology, Medical School, University of São Paulo, São Paulo, SP, Brazil.
  • Gerstenhaber JA; Department of Bioengineering, Temple University, Philadelphia, PA, USA.
  • Raia S; Department of Surgery, Medical School, University of São Paulo, São Paulo, SP, Brazil.
  • Lelkes PI; Department of Bioengineering, Temple University, Philadelphia, PA, USA.
  • Zatz M; Human Genome and Stem-Cell Research Center (HUG-CEL), Department of Genetics and Evolutionary Biology, Institute of Biosciences, University of São Paulo, São Paulo, SP, Brazil. mayazatz@usp.br.
Stem Cell Res Ther ; 10(1): 258, 2019 08 15.
Article em En | MEDLINE | ID: mdl-31416480

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Organoides / Regulação da Expressão Gênica / Fator de Crescimento Transformador beta / Proteínas Wnt / Células-Tronco Pluripotentes Induzidas / Fígado Limite: Adult / Female / Humans / Male Idioma: En Revista: Stem Cell Res Ther Ano de publicação: 2019 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Organoides / Regulação da Expressão Gênica / Fator de Crescimento Transformador beta / Proteínas Wnt / Células-Tronco Pluripotentes Induzidas / Fígado Limite: Adult / Female / Humans / Male Idioma: En Revista: Stem Cell Res Ther Ano de publicação: 2019 Tipo de documento: Article