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Cost-effectiveness of the prevention of adhesions and adhesive small bowel obstruction after colorectal surgery with adhesion barriers: a modelling study.
Krielen, Pepijn; Grutters, Janneke P C; Strik, Chema; Ten Broek, Richard P G; van Goor, Harry; Stommel, Martijn W J.
Afiliação
  • Krielen P; 1Department of Surgery, Radboud University Medical Center, Nijmegen, The Netherlands.
  • Grutters JPC; 2Department for Health Evidence, Radboud University Medical Center, Nijmegen, The Netherlands.
  • Strik C; 3Department of Operating Rooms, Radboud University Medical Center, Nijmegen, The Netherlands.
  • Ten Broek RPG; 1Department of Surgery, Radboud University Medical Center, Nijmegen, The Netherlands.
  • van Goor H; 1Department of Surgery, Radboud University Medical Center, Nijmegen, The Netherlands.
  • Stommel MWJ; 1Department of Surgery, Radboud University Medical Center, Nijmegen, The Netherlands.
World J Emerg Surg ; 14: 41, 2019.
Article em En | MEDLINE | ID: mdl-31428188
ABSTRACT

Background:

Adhesion barriers have proven to reduce adhesion-related complications in colorectal surgery. However, barriers are seldom applied. The aim of this study was to determine the cost-effectiveness of adhesion barriers in colorectal surgery.

Methods:

A decision-tree model was developed to compare cost-effectiveness of no adhesion barrier with the use of an adhesion barrier in open and laparoscopic surgery. Outcomes were incidence of clinical consequences of adhesions, direct healthcare costs, and incremental cost-effectiveness ratio per adhesion prevented. Deterministic and probabilistic sensitivity analyses were performed.

Results:

Adhesion barriers reduce adhesion incidence and incidence of adhesive small bowel obstruction in open and laparoscopic surgery. Adhesion barriers in open surgery reduce costs compared to no adhesion barrier ($4376 versus $4482). Using an adhesion barrier in laparoscopic procedures increases costs by $162 ($4482 versus $4320). The ICER in the laparoscopic cohort was $123. Probabilistic sensitivity analysis showed 66% and 41% probabilities of an adhesion barrier reducing costs for open and laparoscopic colorectal surgery, respectively.

Conclusion:

The use of adhesion barriers in open colorectal surgery is cost-effective in preventing adhesion-related problems. In laparoscopic colorectal surgery, an adhesion barrier is effective at low costs.
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 1_ASSA2030 Base de dados: MEDLINE Assunto principal: Procedimentos Cirúrgicos do Sistema Digestório / Aderências Teciduais / Análise Custo-Benefício Tipo de estudo: Etiology_studies / Health_economic_evaluation / Incidence_studies / Prognostic_studies Limite: Humans Idioma: En Revista: World J Emerg Surg Ano de publicação: 2019 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 1_ASSA2030 Base de dados: MEDLINE Assunto principal: Procedimentos Cirúrgicos do Sistema Digestório / Aderências Teciduais / Análise Custo-Benefício Tipo de estudo: Etiology_studies / Health_economic_evaluation / Incidence_studies / Prognostic_studies Limite: Humans Idioma: En Revista: World J Emerg Surg Ano de publicação: 2019 Tipo de documento: Article