Assemblies of calcium/calmodulin-dependent kinase II with actin and their dynamic regulation by calmodulin in dendritic spines.

Wang, Qian; Chen, Mingchen; Schafer, Nicholas P; Bueno, Carlos; Song, Sarah S; Hudmon, Andy; Wolynes, Peter G; Waxham, M Neal; Cheung, Margaret S

Wang, Qian; Chen, Mingchen; Schafer, Nicholas P; Bueno, Carlos; Song, Sarah S; Hudmon, Andy; Wolynes, Peter G; Waxham, M Neal; Cheung, Margaret S.

Afiliação

Wang Q; Center for Theoretical Biological Physics, Rice University, Houston, TX 77005.
Chen M; Center for Theoretical Biological Physics, Rice University, Houston, TX 77005.
Schafer NP; Center for Theoretical Biological Physics, Rice University, Houston, TX 77005.
Bueno C; Center for Theoretical Biological Physics, Rice University, Houston, TX 77005.
Song SS; Department of Neurobiology and Anatomy, The University of Texas Health Science Center at Houston McGovern Medical School, Houston, TX 77030.
Hudmon A; Medicinal Chemistry and Molecular Pharmacology, Purdue University College of Pharmacy, West Lafayette, IN 47907.
Wolynes PG; Center for Theoretical Biological Physics, Rice University, Houston, TX 77005; pwolynes@rice.edu m.n.waxham@uth.tmc.edu mscheung@uh.edu.
Waxham MN; Department of Chemistry, Rice University, Houston, TX 77005.
Cheung MS; Department of Neurobiology and Anatomy, The University of Texas Health Science Center at Houston McGovern Medical School, Houston, TX 77030; pwolynes@rice.edu m.n.waxham@uth.tmc.edu mscheung@uh.edu.

Proc Natl Acad Sci U S A ; 116(38): 18937-18942, 2019 09 17.

Article em En | MEDLINE | ID: mdl-31455737

Assuntos

Actinas/metabolismo; Proteína Quinase Tipo 2 Dependente de Cálcio-Calmodulina/metabolismo; Calmodulina/metabolismo; Espinhas Dendríticas/metabolismo; Citoesqueleto de Actina; Actinas/química; Cálcio/química; Cálcio/metabolismo; Proteína Quinase Tipo 2 Dependente de Cálcio-Calmodulina/química; Calmodulina/química; Simulação por Computador; Modelos Moleculares; Ligação Proteica; Domínios Proteicos; Multimerização Proteica

Palavras-chave

CaMKII; actin remodeling; calmodulin

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Calmodulina / Actinas / Espinhas Dendríticas / Proteína Quinase Tipo 2 Dependente de Cálcio-Calmodulina Tipo de estudo: Prognostic_studies Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2019 Tipo de documento: Article

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